Reflections on TRP and TP/GFR in the definition of renal phosphate loss: conceptual review.

Background: Fractional tubular reabsorption of phosphate (TRP) has been used for over 60 years to establish the existence of renal phosphate loss. It is a parameter of corrected volume per decilitre of glomerular filtration rate (GFR). Later, a mass parameter per dl GFR called TP/GFR (tubular PO reabsorption per dl GFR) was devised which some authors have sought to substitute for TRP.

Evolution of bone mineral density in patients with idiopathic hypercalciuria: a 20-year longitudinal study.

Background: Several recent studies reported bone mineral density (BMD) reduction in pediatric patients with idiopathic hypercalciuria (IH). This longitudinal study aimed to evaluate BMD evolution in IH patients through three bone densitometry studies conducted over 20 years on average. A second objective was to evaluate urine calcium and citrate excretion during this period.