Publications by authors named "Maria Carmen Zarate-Hernandez"
Rev Alerg Mex
January 2015
Article Synopsis
- Adverse reactions to food have increased globally, with food allergies affecting 2-4% of adults and 6-8% of children, displaying a range of symptoms from mild to severe, necessitating allergen testing.
- The study aimed to profile patients with suspected food allergies in Mexico and analyzed data from 1,971 patients, revealing no gender differences but a bimodal age distribution with peaks at ages 2 and 35.
- Most patients had prior respiratory allergies, 80% experienced symptoms before consultation, and skin reactions were most common, with only 5% reporting anaphylaxis; thus, proper diagnostic confirmation is crucial despite high suspicion.
J Clin Immunol
February 2014
Article Synopsis
- Hyper-IgM syndrome (HIGM) is a condition with high IgM and low levels of other immunoglobulins (IgG, IgA, IgE) that can lead to a variety of infections.
- A study from the HIGM syndrome Registry in Latin America found molecular defects in 37 out of 58 patients, primarily CD40 ligand deficiency in 35 cases, which was linked to severe respiratory and opportunistic infections.
- This research provides new insights into the genetic and clinical characteristics of HIGM syndrome in Latin America, including previously unreported mutations and the success of bone marrow transplants for some patients.
