Publications by authors named "Maria Carmen Fernandez Cano"
Early identification of patients at risk of developing severe acute pancreatitis (SAP) is still an issue. Dynamic assessment of clinical and laboratory parameters within the first 48 h of admission may offer valuable insights into the prediction of unfavorable outcomes such as SAP and death. A prospective observational study was conducted on a cohort of patients admitted for AP at a tertiary referral hospital.
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- A study examined the persistence of adalimumab biosimilars compared to the original drug, analyzing data from 104 patients grouped by the type of medication received.
- Results showed that the biosimilars had higher persistence rates after 12 months, with no significant differences in mild adverse events across groups, but a higher occurrence of severe events in those who switched from the original to the biosimilar.
- Overall, biosimilars proved to be a cost-effective and clinically equivalent option for treating inflammatory bowel disease (IBD), without negatively impacting patient outcomes, supporting their use in healthcare sustainability.
Background: tofacitinib is a Janus kinase inhibitor approved for the treatment of moderate-severe ulcerative colitis (UC). This study aimed to evaluate its efficacy in a real-life setting.
Methods: a retrospective and multicenter observational study was performed with UC patients treated with tofacitinib.
Background: Endoscopic ultrasound (EUS) is useful in the diagnostic workup of idiopathic acute pancreatitis but its role as a predictor of recurrence has not been thoroughly assessed. Our aim was to study the performance of EUS in idiopathic acute pancreatitis, its impact on the natural history of the disease, and the factors related to recurrence.
Methods: Patients with idiopathic acute pancreatitis referred to our endoscopy unit were enrolled and followed, with assessment of the performance of endoscopic retrograde cholangiopancreatography (ERCP), cholecystectomy, and the incidence of recurrence.