Publications by authors named "Maria C Mac Donnell"
Int J Biol Markers
July 2016
Article Synopsis
- - The study investigates the impact of CD44 and Lewis Y antigen (LeY) on therapy resistance in patients with locally advanced cervical squamous cell carcinoma (LACSCC), showing that these markers relate to tumor behavior and patient outcomes.
- - Data from 126 patients was analyzed, revealing that advanced disease and expression of LeY were linked to poorer survival rates in those treated with standard radiochemotherapy based on cisplatin.
- - While coexpression of CD44 and LeY was not associated with worse outcomes overall, LeY expression specifically indicated shorter disease-free and overall survival in patients receiving radiochemotherapy.
