Evaluating Chatbot responses to patient questions in the field of glaucoma.

Objective: The aim of this study was to evaluate the accuracy, comprehensiveness, and safety of a publicly available large language model (LLM)-ChatGPT in the sub-domain of glaucoma.

Design: Evaluation of diagnostic test or technology.

Subjects Participants And/or Controls: We seek to evaluate the responses of an artificial intelligence chatbot ChatGPT (version GPT-3.

Three-Year Outcomes of the Paul Glaucoma Implant for Treatment of Glaucoma.

Prcis: In our case series, the 3-year failure for Paul Glaucoma Implant (PGI) implantation was 14.6%. At 3 years postoperatively, there was a significant reduction in mean intraocular pressure (IOP) and the number of glaucoma medications used.

Use of anterior segment imaging and direct cyclopexy repair of cyclodialysis cleft.

We aim to describe different imaging modalities to localize cyclodialysis clefts and direct cyclopexy repair of cyclodialysis clefts. We reviewed the record of a patient with traumatic cyclodialysis cleft who underwent direct cyclopexy retrospectively. Preoperative and postoperative visual acuity and intraocular pressure (IOP) were recorded.

Two-Year Outcomes of the Paul Glaucoma Implant for Treatment of Glaucoma.

Purpose: To determine 2-year efficacy of the PAUL Glaucoma Implant (PGI), a novel glaucoma tube shunt in patients with advanced glaucoma.

Participants: Patients with glaucoma refractory to maximum medical therapy or previous failed glaucoma surgery.

Methods: Retrospective review of all patients who had underwent PGI implantation in a single tertiary institution between May 1, 2017 and March 30, 2021.

Comparison of refractive outcomes after combined cataract and glaucoma surgery: trabeculectomy and glaucoma drainage device implantation.

Purpose: To investigate the refractive outcome of combined cataract surgery and glaucoma drainage device (GDD) implantation compared with trabeculectomy and cataract surgery.

Setting: Department of Ophthalmology, National University Health System, Singapore.

Design: Retrospective cohort study.

One-Year Outcomes of Micropulse Cyclophototherapy for Primary Open-angle Glaucoma.

Precis: In primary open-angle glaucoma (POAG), micropulse trans-scleral cyclophototherapy (MPTCP) is effective in lowering intraocular pressure (IOP), but its effects are not permanent. Hence, it can serve as a temporizing measure before definitive glaucoma surgery.

Purpose: There is limited data on MPTCP in POAG.

Micropulse P3™ (MP3) Laser for Glaucoma: An Innovative Therapy.

Aquino MC, Lim D, Chew PTK. Micropulse P3™(MP3) Laser for Glaucoma: An Innovative Therapy. J Curr Glaucoma Pract 2018;12(2):51-52.

Quantitative assessment of changes in anterior segment morphology after argon laser peripheral iridoplasty: findings from the EARL study group.

Importance: Argon laser peripheral iridoplasty (ALPI) could be effective in widening residual angle closure following laser peripheral iridotomy (LPI).

Background: We investigated changes in angle parameters following ALPI and its safety profile in this study.

Design: Retrospective, observational case series.

Outcomes and Complications of Scleral-Fixated Intraocular Lens Combined with Ahmed Tube Surgery.

Background: To evaluate the outcome and complications of transscleral suture-fixated posterior chamber intraocular lens (PCIOL) implantation combined with Ahmed glaucoma valve (AGV) surgery in Asian eyes.

Design: This was a retrospective study that included 22 eyes from 22 participants. The surgeries were performed at Singapore's National University Hospital.

Surgical Treatment of Angle-Closure Glaucoma.

Advances in anterior segment imaging modalities have contributed new insights towards a better understanding of the various mechanisms of angle-closure glaucoma (ACG). This development is key to good decision making when confronted with angle-closure patients needing appropriate therapy. Surgical management of ACG remains an integral part of glaucoma patient care.

Automated anterior segment OCT image analysis for Angle Closure Glaucoma mechanisms classification.

Background And Objectives: Angle closure glaucoma (ACG) is an eye disease prevalent throughout the world. ACG is caused by four major mechanisms: exaggerated lens vault, pupil block, thick peripheral iris roll, and plateau iris. Identifying the specific mechanism in a given patient is important because each mechanism requires a specific medication and treatment regimen.

Complex wavelet based quality assessment for AS-OCT images with application to Angle Closure Glaucoma diagnosis.

Background And Objectives: Angle closure disease in the eye can be detected using time-domain Anterior Segment Optical Coherence Tomography (AS-OCT). The Anterior Chamber (AC) characteristics can be quantified from AS-OCT image, which is dependent on the image quality at the image acquisition stage. To date, to the best of our knowledge there are no objective or automated subjective measurements to assess the quality of AS-OCT images.

Feasibility study of sustained-release travoprost punctum plug for intraocular pressure reduction in an Asian population.

Purpose: To investigate the efficacy and safety of a punctum plug-based sustained drug release system for a prostaglandin analog, travoprost (OTX-TP), for intraocular pressure (IOP) reduction in an Asian population.

Methods: This is an initial feasibility, prospective, single-arm study involving 26 eyes and a bioresorbable punctum plug containing OTX-TP. An OTX-TP was placed in the vertical portion of the superior or inferior canaliculus of patients with primary open-angle glaucoma or ocular hypertension.

Learning ECOC Code Matrix for Multiclass Classification with Application to Glaucoma Diagnosis.

Classification of different mechanisms of angle closure glaucoma (ACG) is important for medical diagnosis. Error-correcting output code (ECOC) is an effective approach for multiclass classification. In this study, we propose a new ensemble learning method based on ECOC with application to classification of four ACG mechanisms.

Anterior segment morphology after acute primary angle closure treatment: a randomised study comparing iridoplasty and medical therapy.

Purpose: To compare the effect of argon laser peripheral iridoplasty (ALPI) and conventional medical therapy in the immediate treatment of acute primary angle closure (APAC) using anterior segment optical coherence tomography (ASOCT).

Methods: In this single tertiary centre, prospective comparative study, we randomised 30 consecutive patients with unilateral APAC into two groups: ALPI and medical treatment (n=15 each). Immediately before and 1 h after either intervention, ASOCT imaging was performed.

Complications and outcomes of primary phacotrabeculectomy with mitomycin C in a multi-ethnic asian population.

Purpose: To determine the occurrence of intraoperative and postoperative complications up to three years after primary phacotrabeculectomy with intraoperative use of Mitomycin C (MMC) in primary open angle (POAG) and primary angle closure glaucoma (PACG) patients, and the effect of postoperative complications on surgical outcome.

Methods: Retrospective review of 160 consecutive patients with POAG (n = 105) and PACG (n = 55), who underwent primary phacotrabeculectomy with MMC at the National University Hospital, Singapore, from January 1, 2008 to December 31, 2010. Data was collected using a standardized form that included patient demographic information, ocular characteristics and postoperative complications, including hypotony (defined as intraocular pressure < 6 mmHg), shallow anterior chamber (AC) and hyphema.

Cross-Examination for Angle-Closure Glaucoma Feature Detection.

Effective feature selection plays a vital role in anterior segment imaging for determining the mechanism involved in angle-closure glaucoma (ACG) diagnosis. This research focuses on the use of redundant features for complex disease diagnosis such as ACG using anterior segment optical coherence tomography images. Both supervised [minimum redundancy maximum relevance (MRMR)] and unsupervised [Laplacian score (L-score)] feature selection algorithms have been cross-examined with different ACG mechanisms.

Micropulse versus continuous wave transscleral diode cyclophotocoagulation in refractory glaucoma: a randomized exploratory study.

Background: The aim of this study was to compare the efficacy and safety of micropulse and continuous wave diode transscleral cyclophotocoagulation in refractory glaucoma.

Design: Randomized, comparative, exploratory study in a tertiary hospital setting.

Participants: Patients with refractory, end-stage glaucoma.

A prospective comparison of chronic primary angle-closure glaucoma versus primary open-angle glaucoma in Singapore.

Introduction: To describe the optic disc, visual field and ocular characteristics of a consecutive cohort of Asian patients with chronic primary angle-closure glaucoma (CPACG), and compare them with those having primary open-angle glaucoma (POAG).

Methods: In a prospective comparative case series of new patients with POAG or CPACG in Singapore, all patients underwent visual acuity assessment, slit-lamp examination, tonometry, gonioscopy, refraction, Heidelberg Retina Tomograph (HRT) and Humphrey visual field (HVF) assessment.

Results: 98 patients were enrolled (POAG n = 48; CPACG n = 50).