Publications by authors named "Maria Belen Gonzalez"
Article Synopsis
- * Between November 2020 and April 2021, the B.1.1.28 sublineage, designated as P.6, emerged as the dominant variant in Uruguay, featuring specific spike mutations (Q675H and Q677H) that may increase its transmissibility.
- * By April 2021, lineage P.6 was supplanted by the more concerning variant P.1, highlighting the need for ongoing global monitoring of the mutations present in different viral strains.
Background: The impact of such recommendations after their implementation of guidelines has not usually been evaluated. Herein, we assessed the impact and compliance with the Spanish Oncology Genitourinary Group (SOGUG) Guidelines for toxicity management of targeted therapies in metastatic renal cell carcinoma (mRCC) in daily clinical practice.
Methods: Data on 407 mRCC patients who initiated first-line targeted therapy during the year before and the year after publication and implementation of the SOGUG guideline program were available from 34 Spanish Hospitals.
Background: Patients with transitional cell carcinoma of the urothelial tract (TCCU) who fail initial platinum-based chemotherapy for advanced disease represent a challenge in daily clinical practice. Vinflunine is approved by the European Medicine Agency (EMA) but, up to now, limited experience has been reported outside clinical trials.
Methods: We assessed the efficacy and safety of vinflunine in an unselected group of 102 consecutive patients with metastatic TCCU.
Background: The purpose of this study was to determine the prevalence of hypertension, cardiovascular risk factors and target organ damage using baseline data from the EVA study.
Methods: EVA is a 5-year multicentre prospective study of women aged between 40 and 70 years attending primary care centres in a rural-urban area in the north of Spain. The recruitment period was between October 2009 and January 2010.
Objective: To identify chromosomal gains and losses in sporadic parathyroid adenomas (PAs).
Methods: Fourteen sporadic PAs were studied by comparative genomic hybridization (CGH).
Results: The fourteen studied PAs showed chromosomal imbalances.