Melanocyte transplantation for the treatment of vitiligo: effects of different surgical techniques.

This paper presents the results of a pilot clinical trial study, conducted on 11 patients with stable vitiligo at the vitiligo outpatient clinic of The Unicamp University Hospital, between March 2000 and December 2001. This study was in accordance with the ethical standards of the Institutional Review Board. The patients were concomitantly treated with four different types of surgical techniques in 44 areas randomly chosen.

Sjögren-Larsson syndrome: biochemical defects and follow up in three cases.

Sjögren-Larsson syndrome is a rare disorder that consists of congenital ichthyosis and neurological symptoms due to an enzymatic defect of fatty aldehyde dehydrogenase in the fatty alcohol cycle. We report three cases of Sjögren-Larsson syndrome in which the primary biochemical defect was established in two patients (patient 2: 175 pmol/min/mg; patient 3: 103 pmol/min/mg protein enzimatic activity in fibroblasts in skin, while normal controls were 8,860 +/- 1,624, n: 22 ). A dietary program was proposed: reduced total fatty intake at 30% of total calories, n-3 and n-6 acids (canola oil) as well as unsaturated fatty acids (Milupan milk).