[Neonatal seizures in a tertiary neonatal intensive care unit].

Introduction: Seizures are frequent in the neonatal period. They can be idiopathic, be caused by organic brain anomalies or by metabolic disturbances.

Objective: Evaluation of the etiologic diagnosis and clinical evolution of the newborns with neonatal seizures admitted at one tertiary neonatal intensive care unit.

Vitamin A in prevention of bronchopulmonary dysplasia.

Bronchopulmonary dysplasia (BPD) remains one of the most serious challenges in the care of the very preterm infants, affecting approximately one-quarter of infants born < 1500g birth weight and 30% < 1000g. Oxygen toxicity may contribute to its pathogenesis. Vitamin A concentrations are lower in BPD infants which may result in a reduction of the antioxidant protection.

Vitamin A in Prevention of Bronchopulmonary Dysplasia.

Bronchopulmonary dysplasia (BPD) remains one of the most serious challenges in the care of the very preterm infants, affecting approximately one-quarter of infants born <1500g birth weight and 30% <1000g. Oxygen toxicity may contribute to its pathogenesis. Vitamin A concentrations are lower in BPD infants which may result in a reduction of the antioxidant protection.

Respiratory outcomes and atopy in school-age children who were preterm at birth, with and without bronchopulmonary dysplasia.

Objective: To assess pulmonary function and the prevalence of atopy in school-age children who were very low birth weight as infants and to compare those who had bronchopulmonary dysplasia to those who did not.

Method: We studied 85 (39 male and 46 female) at a mean age of 84 (range, 62 to 107) months who were very low birth weight infants. Bronchopulmonary dysplasia was defined as oxygen dependency at 36 weeks gestational age.

Prospective validation of a novel strategy for assessing risk of significant hyperbilirubinemia.

Objective: Our aim was to validate a strategy for assessing the risk of significant hyperbilirubinemia in newborns with gestational ages of ≥35 weeks by combining predischarge bilirubin percentile data with gestational age data, for a European, predominantly white population.

Methods: We conducted a prospective cohort study with 463 newborns with gestational ages of ≥35 weeks who were admitted to the well-infant nursery. Total bilirubin levels were measured daily until discharge and once after discharge, between the third and eighth days of life, by using a Bilicheck device (Respironics, Murrysville, PA).

[Successful caspofungin treatment of invasive refractory candidiasis in the extremely low birthweight neonate].

Introduction: Multiresistant Candida septicaemia is an increasing problem in Neonatal Intensive Care Units worldwide. Caspofungin is a new antifungal drug licensed in Portugal for use in children since September 2008, with limited experience in newborns.

Case Report: Preterm female, 26 weeks gestational age, born by vaginal delivery, with 780g birthweight and Apgar score 8/9.

[Newborn with nonimmune hydrops fetalis - the experience of a tertiary center].

Background And Aims: Nonimmune hydrops fetalis is a rare affection that can result from several disorders. Notwithstanding with the advances in the diagnosis and treatment, its morbidity and mortality are still very high. The purpose of this study was to characterize the newborn population with nonimmune hydrops fetalis admitted to our unit during the last ten years.

[Octreotide for conservative management of postoperative chylothorax in the neonate].

Chylothorax is a possible complication after thoracotomy. Treatment is initially conservative and includes drainage and correction of nutritional losses. Surgical treatment is reserved for cases not responsive to medical measures.