Celiac disease in a large cohort of children and adolescents with recurrent headache: A retrospective study.

Background: The clinical picture of celiac disease is changing with the emergence of subclinical forms and growing evidence reporting associated neurological disorders.

Aims: To establish the prevalence of celiac disease in children suffering from recurrent headache.

Methods: In our retrospective study we collected charts from 1131 children attending our tertiary care Centre for Paediatric Headache over the period 2001-2012.

Coeliac disease screening among a large cohort of overweight/obese children.

Coeliac disease (CD) is a chronic, gluten-dependent enteropathy with a prevalence of approximately 1% in Western countries. Up to now, CD has been described only in sporadic cases of obesity. Our study aimed to evaluate retrospectively CD prevalence in a large series of overweight/obese children and adolescents.

Anti-transglutaminase immunoreactivity and histological lesions of the duodenum in coeliac patients.

Coeliac disease (CD) is characterized by several markers, including anti-transglutaminase auto-antibodies (tTGAb) directed against multiple epitopes of the gliadin protein. We aimed to investigate the correlation among CD duodenal lesions, tTGAb titres and the immunoreactivity against tTG constructs. A total of 345 CD patients (209 females, 136 males, overall median age: 7.