Examination of the Corneal Endothelium in Patients With Congenital Aniridia With a PAX6 Mutation Using In Vivo Confocal Laser Scanning Microscopy.

Purpose: In PAX6 syndrome, it is still not clear, whether prenatally, parallel to the iris tissue developmental anomaly, there is neural ectodermal, neural crest, or mesodermal cell deposition at the corneal endothelium, affecting endothelial structure and function. In addition, because of the postnatal corneal inflammation and commonly appearing secondary glaucoma, progressive endothelial changes are expected. Our purpose was to study the corneal endothelium in subjects with PAX6 aniridia, using in vivo confocal laser scanning microscopy.

Examination of Subbasal Nerve Plexus and Central Corneal Stromal Microstructure in Subjects With Congenital Aniridia, Using Confocal Laser Scanning Microscopy.

Purpose: During life up to 70% of aniridia subjects develop aniridia-associated keratopathy (AAK). AAK is characterized by limbal stem cell insufficiency, impaired corneal epithelial cell differentiation and abnormal cell adhesion, which leads to centripetal spreading vascularization, conjunctivalization, and thickening of the cornea. Our aim was to examine the subbasal nerve plexus and central corneal stromal microstructure in subjects with congenital aniridia, using confocal laser scanning microscopy CLSM.

[Congenital aniridia patients' experience on their visual impairment in Hungary.].

Introduction: Aniridia is a rare congenital panocular disease associated with varying degrees of visual acuity impairment.

Objective: To assess the experiences of congenital aniridia patients in Hungary, with visual impairment using a questionnaire developed by the ANIRIDIA-NET.

Patients And Method: Patients completed the Hungarian version of the 20-item ANIRIDIA-NET questionnaire with our assistance.

[Congenital aniridia - Hungarian data of a spectrum disease].

Introduction: Congenital aniridia is a rare disease, characterised by the complete or partial absence of the iris, but lesions may be present in all structures of the eye.

Objective: To determine the prevalence of ocular diseases in congenital aniridia by analyzing patients from a Hungarian centre.

Patients And Methods: Patients at the Department of Ophthalmology of Semmelweis University, examined between October 2005 and May 2022, have been included.

[The impact of district nurses in screening visual impairments].

Introduction: The children's physical and mental health is determinative for the whole society. Parents, teachers, district nurses, and doctors share the duty to ensure their uninterrupted visual development. District nurses compose key elements in connecting families and health care providers, since they have the chance to detect any visual anomalies, and to refer the children to a pediatrician, ophthalmologist, or a neurologist.

[Axenfeld–Rieger syndrome: ophthalmological and dental diagnostic and therapeutic options].

Összefoglaló. Az Axenfeld-Rieger-szindróma ritka betegség. A közlemény bemutatja a klinikai megjelenési formáit, a diagnosztikus és terápiás lehetőségeket.

Preoperative biometry data of eyes with unilateral congenital cataract.

Purpose: To investigate the differences in biometry data of eyes with unilateral congenital cataract and the contralateral normal eyes in pediatric patients.

Setting: Pediatric Ophthalmology Division, Ophthalmology Department, Semmelweis University in Budapest, Hungary.

Design: Retrospective case series.

Starflo glaucoma implant: early experience in Hungary.

Aim: To present the early experience with the implantation technique, safety and efficiency of STARflo device for open angle glaucoma (OAG).

Methods: referring intra- and postoperative clinical experience with a series of seven cases in three glaucoma centers in Hungary.

Results: No intraoperative complications were observed.

Comparison of the current and a new RTVue OCT software version for detection of ganglion cell complex changes due to cataract surgery.

The purpose was to compare the current (6.3) and a novel software version (6.12) of the RTVue-100 optical coherence tomograph (RTVue OCT) for ganglion cell complex (GCC) and retinal nerve fibre layer thickness (RNFLT) changes after phacoemulsification in healthy cataract eyes, and to investigate whether version 6.

The role of complement activation in the pathogenesis of Fuchs' dystrophy.

Purpose: Inflammation can be an etiologic factor of Fuchs' dystrophy according to previous studies. Our aim was to analyse the activation of the complement system in the aqueous humor in this pathological condition.

Methods: 100 μl aqueous humor sample was taken during keratoplasty of 11 Fuchs' dystrophic patients and during phacoemulsification surgery of 18 control patients.

Complement activation in the aqueous humor of pseudophakic bullous keratopathy patients.

Background/aims: According to some studies, inflammation is a potential etiological factor in pseudophakic bullous keratopathy (PBK). Our aim was to obtain information on the activation of the complement system in the aqueous humor in this disorder.

Methods: Aqueous humor samples were collected during keratoplasty of 12 PBK patients, as well as during phacoemulsification surgery of 18 control patients.

Increased tear osmolarity in patients with severe cases of conjunctivochalasis.

Purpose: To evaluate and compare tear osmolarity in different grades of conjunctivochalasis.

Patients And Methods: Forty subjects divided into four groups based on grading of conjunctivochalasis by lid-paralell conjunctival fold (LIPCOF) test and tear osmolarity evaluated by TearLab osmometer. Schirmer test, tear film break up time (BUT) and vital staining were also performed.

Bacterial contamination in the anterior chamber after povidone-iodine application and the effect of the lens implantation device.

Purpose: To assess the incidence of anterior chamber bacterial contamination during cataract surgery, and compare results of injector implantation and forceps implantation of foldable intraocular lenses (IOLs).

Setting: Department of Ophthalmology and Institute of Medical Microbiology, Semmelweis University, Budapest, Hungary.

Methods: This prospective randomized controlled clinical study comprised 97 eyes of 96 patients.