Design and rationale of the medical students learning weight management counseling skills (MSWeight) group randomized controlled trial.

Physicians have an important role addressing the obesity epidemic. Lack of adequate teaching to provide weight management counseling (WMC) is cited as a reason for limited treatment. National guidelines have not been translated into an evidence-supported, competency-based curriculum in medical schools.

Binge alcohol consumption 18 h after induction of sepsis in a mouse model causes rapid overgrowth of bacteria, a cytokine storm, and decreased survival.

Alcohol abuse increases vulnerability to infections and infection-related mortality. In previous studies, we found that acute alcohol abuse in a binge-drinking model in mice decreased resistance to bacterial sepsis when alcohol was administered near the time of bacterial challenge. In the present study, we investigated the effects of alcohol administered later in the course of sepsis (18 h after injection of Escherichia coli).

[Epidemiological study in mental health: health services use and perception of social support].

Objective The general aim of this non-probabilistic epidemiologic study is to detect the levels of mental health symptoms and social support for the residents of two neighborhoods in the General Belgrano district in Guaymallén, Mendoza Province, Argentina. Methods A random sample of 62 adults was selected, in which the proportionality of age and sex were conserved in each quota. Each person was interviewed in his/her house using the Cuestionario Epidemiológico de Sintomatología Mental [Epidemiological Questionnaire on Mental Health Symptoms] (CESIM) and the Cuestionario de Apoyo Social Comunitario Percibido [Questionnaire on Perceived Community Social Support].

Infection of Murine Macrophages by Salmonella enterica Serovar Heidelberg Blocks Murine Norovirus Infectivity and Virus-induced Apoptosis.

Gastroenteritis caused by bacterial and viral pathogens constitutes a major public health threat in the United States accounting for 35% of hospitalizations. In particular, Salmonella enterica and noroviruses cause the majority of gastroenteritis infections, with emergence of sporadic outbreaks and incidence of increased infections. Although mechanisms underlying infections by these pathogens have been individually studied, little is known about the mechanisms regulating co-infection by these pathogens.

Lower extremity limb salvage with cryoplasty: a single-center cohort study.

Endovascular techniques have been playing an increasing role in managing lower extremity chronic critical limb ischemia (CLI) in patients considered poor or non-candidates for surgical revascularization secondary to co-morbidities such as coronary artery disease, uncontrolled hypertension, diabetes mellitus or inadequate conduit. This study reviews our recent clinical experience in the treatment of peripheral artery disease solely using cryoplasty. A retrospective cohort study was performed.

The effects of freezing versus supercooling on vascular cells: implications for balloon cryoplasty.

Purpose: To investigate the effects of supercooling, a phase whereby cells are below 0 degrees C but still in a liquid state, and freezing, the phase when cells become solid, of vascular cells in culture.

Materials And Methods: Bovine aortic endothelial cells and smooth muscle cells were supercooled to -10 degrees C with or without freezing for 3, 30, or 60 seconds and then rewarmed to 37 degrees C for 24 hours. Viability was assessed by means of trypan blue exclusion, and apoptosis was assessed with the TUNEL (terminal deoxynucleotidyl transferase-mediated dUTP nick-end labeling) assay.

Cryosurgery: A review.

Cryosurgery dates back to the 19th century, with the description of the benefits of local application of cooling for conditions such as pain control. Once commercial liquefied gases became available, more progress was made in the use of cryotherapy for localized lesions. As understanding of disease response to freezing increased, safer techniques for performing freezing procedures helped prepare its clinical application in different clinical situations, such as prostate disease and bronchial cancers.