Polyoxopalladates encapsulating 8-coordinated metal ions, [MO8Pd(II)12L8]n- (M = Sc3+, Mn2+, Fe3+, Co2+, Ni2+, Cu2+, Zn2+, Lu3+; L = PhAsO3(2-), PhPO3(2-), SeO3(2-)).

A total of 16 discrete polyoxopalladates(II) [MO(8)Pd(II)(12)L(8)](n-), with a metal ion M encapsulated in a cuboid-shaped {Pd(12)O(8)L(8)} cage, have been synthesized: the phenylarsonate-capped series (1) L = PhAsO(3)(2-), M = Sc(3+) (ScPhAs), Mn(2+) (MnPhAs), Fe(3+) (FePhAs), Co(2+) (CoPhAs), Ni(2+) (NiPhAs), Cu(2+) (CuPhAs), Zn(2+) (ZnPhAs); the phenylphosphonate-capped series: (2) L = PhPO(3)(2-), M = Cu(2+) (CuPhP), Zn(2+) (ZnPhP); and the selenite-capped series (3) L = SeO(3)(2-), M = Mn(2+) (MnSe), Fe(3+) (FeSe), Co(2+) (CoSe), Ni(2+) (NiSe), Cu(2+), (CuSe), Zn(2+) (ZnSe), Lu(3+) (LuSe)). The polyanions were prepared in one-pot reactions in aqueous solution of [Pd(3)(CH(3)COO)(6)] with an appropriate salt of the metal ion M, as well as PhAsO(3)H(2), PhPO(3)H(2), and SeO(2), respectively, and then isolated as hydrated sodium salts Na(n)[MO(8)Pd(II)(12)L(8)]·yH(2)O (y = 10-37). The compounds were characterized in the solid state by IR spectroscopy, single-crystal XRD, elemental and thermogravimetric analyses.

Synthesis and biological activity of organoantimony(III)-containing heteropolytungstates.

Three discrete organoantimony(III)-containing heteropolytungstates [(PhSb(III))(4)(A-α-Ge(IV)W(9)O(34))(2)](12-) (1), [(PhSb(III))(4)(A-α-P(V)W(9)O(34))(2)](10-) (2), and [{2-(Me(2)NCH(2)C(6)H(4))Sb(III)}(3)(B-α-As(III)W(9)O(33))](3-) (3) have been synthesized in one-pot reactions in aqueous medium using the appropriate lacunary heteropolyanion precursor and organoantimony(III) source. Polyanions 1-3 were isolated as hydrated salts, (NH(4))(12)[(PhSb(III))(4)(A-α-Ge(IV)W(9)O(34))(2)]·20H(2)O (1a), Rb(9)Na[(PhSb(III))(4)(A-α-P(V)W(9)O(34))(2)]·20H(2)O (2a), and Rb(3)[{2-(Me(2)NCH(2)C(6)H(4))Sb(III)}(3)(B-α-As(III)W(9)O(33))]·7H(2)O (3a). The compounds 1a-3a were fully characterized in the solid state using infrared (IR) spectroscopy, single-crystal XRD, and thermogravimetric and elemental analyses.

Polyoxometalates as potent and selective inhibitors of alkaline phosphatases with profound anticancer and amoebicidal activities.

The biological significance of polyoxometalates is well renowned owing to their anticancer, antiviral and antibiotic properties. Here another therapeutic aspect of polyoxometalates has been explored as alkaline phosphatase inhibitors along with the remarked anticancer and amoebicidal properties. Synthesis and inhibitory studies of a set of seven polyoxotungstates against two major isozymes of alkaline phosphatase i.

3 d metal ions in highly unusual eight-coordination: the phosphate-capped dodecapalladate(II) nanocube.

Trapped in a noble cube: A novel family of noble metalates has been discovered in which a 3d metal ion M (M = Mn(II), Fe(III), Co(II), Cu(II), Zn(II)) is encapsulated by a 12 palladium-oxo cage {Pd(12)O(32)}, which is capped by eight phosphate groups. Such discrete nanocubes were further investigated by EPR spectroscopy, electrochemistry, and in homogeneous hydrogenation catalysis.