Cow's milk protein allergy; new knowledge from a multidisciplinary perspective.

In recent decades, a higher prevalence, persistence, and severity of cow's milk protein allergy (CMPA) have been observed. Different hypotheses have been proposed in relation to potential responsible mechanisms, with emphasis on the role of the microbiota in the induction and maintenance of immune tolerance as well as the importance of establishing a healthy microbiota in an early manner through the promotion of breastfeeding, vaginal delivery, rational use of antibiotics and proton pump inhibitors, along with an early introduction of varied foods. The use of probiotics and allergenspecific immunotherapy (AIT) come up as the treatment strategies with the greatest evidence in favor of tolerance acquisition.

Epidemiological study of food allergy in a population of Argentine children.

Introduction: Food allergies affect mostly children in their first years of life. Epidemiological data obtained in Argentina are scarce.

Objectives: To determine offending foods and describe the prevalence and characteristics of patients with food allergy in an Argentine pediatric population.

Prevalence of cow's milk protein allergy among children in a university community hospital.

Introduction: Cow's milk protein allergy (CMPA) is the most common food allergy in pediatrics. In Argentina, the prevalence of this disease has been evaluated in a few trials.

Objectives: To estimate the prevalence of CMPA and describe its variation throughout a period of 11 years.