Assessing the Relevance of Non-molecular Prognostic Systems for Myelodysplastic Syndrome in the Era of Next-Generation Sequencing.

Background: The Molecular International Prognostic Scoring System (IPSS-M) has improved the prediction of clinical outcomes for myelodysplastic syndromes (MDS). The Artificial Intelligence Prognostic Scoring System for MDS (AIPSS-MDS), based on classical clinical parameters, has outperformed the IPSS, revised version (IPSS-R). For the first time, we validated the IPSS-M and other molecular prognostic models and compared them with the established IPSS-R and AIPSS-MDS models using data from South American patients.

PH negative acute lymphoblastic leukemia in adolescents and young adults treated according a MRD adapted BFM ALL IC 2009 protocol: Argentine real-world data on 171 patients.

Intensified pediatric chemotherapy regimens to treat adolescents and young adults (AYA) patients with Philadelphia negative acute lymphoblastic leukemia (ALL) have been associated with better outcomes. The local BFM 2009-based scheme complements the risk stratification assessing the measurable residual disease (MRD) along the induction phase with increasing levels of sensitivity. The present retrospective multicenter analysis included 171 AYA (15-40 years) patients treated accordingly between 2013 and 2019.

Dietary patterns by cluster analysis in pregnant women: relationship with nutrient intakes and dietary patterns in 7-year-old offspring.

Little is known about how dietary patterns of mothers and their children track over time. The objectives of this study are to obtain dietary patterns in pregnancy using cluster analysis, to examine women's mean nutrient intakes in each cluster and to compare the dietary patterns of mothers to those of their children. Pregnant women (n = 12 195) from the Avon Longitudinal Study of Parents and Children reported their frequency of consumption of 47 foods and food groups.

Dietary intake variations from pre-conception to gestational period according to the degree of industrial processing: A Brazilian cohort.

Objective: To estimate food intake changes from pre-conception to gestational period according to the degree of food processing.

Methods: Prospective cohort conducted in a public health care center in Rio de Janeiro with Brazilian pregnant women (n = 189). A food frequency questionnaire was applied at the first (5(th)-13(th)) and third (30(th)-36(th)) gestational trimesters.

Sociodemographic characteristics determine dietary pattern adherence during pregnancy.

Objective: Sociodemographic factors may affect adherence to specific dietary patterns during pregnancy. The present study aimed to identify dietary patterns during pregnancy and associated factors among Brazilian pregnant women.

Design: A cross-sectional analysis.

Association of Prepregnancy Dietary Patterns and Anxiety Symptoms from Midpregnancy to Early Postpartum in a Prospective Cohort of Brazilian Women.

Background: Adherence to unhealthy dietary patterns may alter the risk of mental disorders during pregnancy and the postpartum period.

Objective: To analyze the association between prepregnancy dietary patterns and prospective variations on anxiety symptoms from midpregnancy to early postpartum.

Methods: A prospective cohort of 207 healthy pregnant women was followed at 5 to 13, 20 to 26, and 30 to 36 gestational weeks, and once at 30 to 45 days postpartum.

Gestational dietary patterns are not associated with blood pressure changes during pregnancy and early postpartum in a Brazilian prospective cohort.

Purpose: To identify gestational dietary patterns and evaluate the association between these patterns and the blood pressure (BP) rate of change during pregnancy and the postpartum.

Methods: Prospective cohort study composed of 191 healthy pregnant women. Systolic BP (SBP) and diastolic BP (DBP) were obtained at the 5th-13th, 20th-26th, 30th-36th gestational weeks, and with 30-45 days postpartum.

Prepregnancy healthy dietary pattern is inversely associated with depressive symptoms among pregnant Brazilian women.

Dietary patterns before pregnancy may be associated with depressive symptomatology during pregnancy. The aim of this study was to identify dietary patterns before pregnancy and to examine the association between these dietary patterns and depressive symptoms during pregnancy. A prospective cohort of 248 healthy pregnant women were followed at 5-13, 20-26, and 30-36 gestational weeks.

Mixed dietary pattern is associated with a slower decline of body weight change during postpartum in a cohort of Brazilian women.

Objective: The aim was to assess the effect of dietary patterns on postpartum body weight change (BWC).

Methods: A Food Frequency Questionnaire (FFQ) with 81 items was applied in 278 women having the first six months after delivery as the time frame. Body weight (BW) was measured at 15 days (baseline) and at 2.

[Adherence to dietary recommendations by the Institute of Medicine and the effect on body weight during pregnancy].

The study's objective was to estimate the effect of adherence to dietary recommendations by the Institute of Medicine (IOM) concerning energy intake and/or macronutrient composition of diet on weight during pregnancy. This was a prospective study with observations at three time points, with a sample of 255 pregnant women. The dependent variable was gestational weight, and the independent variable was dietary adequacy according to IOM recommendations for energy and macronutrient intake, categorized as adequate versus excessive intake.

Assessment of protein intake during pregnancy using a food frequency questionnaire and the effect on postpartum body weight variation.

The aim of this study was to investigate the effect of protein intake during pregnancy on postpartum weight variation. This was a prospective cohort study with 421 women interviewed at 15 days (baseline) and 2, 6, and 9 months postpartum. Data on diet were obtained using the food frequency questionnaire, focusing on the second and third trimesters.

High-protein diet promotes a moderate postpartum weight loss in a prospective cohort of Brazilian women.

Objective: Whether a high-protein (HP) diet promotes body weight loss (BWL) when compared with a low-protein (LP) diet is still unclear. Therefore, we evaluated the effects of an HP diet on BWL during postpartum.

Methods: A food-frequency questionnaire with 81 items was applied at 6 mo after delivery to evaluate the diet of 430 postpartum women aged 18-45 y.

[Dietary patterns among postpartum women treated at a municipal health center in Rio de Janeiro, Brazil].

This study aimed to longitudinally compare nutrient and food intakes by 276 lactating women. Dietary intake was collected using a food frequency questionnaire. Data analysis used the Student-t and ANOVA tests, comparing quantitative and qualitative dietary variation from pregnancy to postpartum.

[Dietary pattern and nutritional status of metalworkers in Rio de Janeiro, Brazil].

Nutritional status, dietary and leisure-time physical activity patterns, and energy intake of 65 male metalworkers aged 19 to 58 years from Rio de Janeiro, Brazil, are described in the context of a surveillance build-up system. Mean body mass index was 25.0 kg/m2 (44.