Publications by authors named "Maria Auxiliadora de Sousa"
Correction to: Trypanosoma rangeli Tejera, 1920, in chronic Chagas' disease patients under ambulatory care at the Evandro Chagas Clinical Research Institute (IPEC-Fiocruz, Brazil).
Parasitol Res
November 2023
Trypanosoma cruzi I genotype among isolates from patients with chronic Chagas disease followed at the Evandro Chagas National Institute of Infectious Diseases (FIOCRUZ, Brazil).
Rev Soc Bras Med Trop
May 2017
Article Synopsis
- Trypanosoma cruzi, the cause of Chagas disease in humans, was isolated from patients at a national infectious disease institute and studied using various methods for species identification.
- The isolates displayed typical T. cruzi characteristics, with successful growth in culture and identification of distinct genotypes (TcI, TcII, and TcVI) through genetic analysis and isoenzyme profiling.
- The study highlights the prevalence of different T. cruzi genotypes in Brazilian patients and their potential link to varied clinical outcomes, emphasizing the need for genotyping in understanding treatment responses and disease manifestations.
Trypanosoma lewisi is a cosmopolitan species originally found in Rattus spp., being nonpathogenic, host-restricted, and transmitted by rat fleas. This species has been recorded as an opportunist blood parasite of human beings mainly in Asia, with a case in Africa.
View Article and Find Full Text PDFSix reference strains of Trypanosoma rangeli from different days of growth in axenic cultures were assayed for susceptibility to complement-mediated lysis by non-immune guinea-pig serum. Their authenticity was also confirmed by isoenzyme analyses. Parasites were incubated with 25% active or 68°C-inactivated serum (37°C, 30 min) for all tests; thereafter the lysis rates were determined.
View Article and Find Full Text PDFSera of patients with systemic lupus erythematosus react with plasmodial antigens and can inhibit the in vitro growth of Plasmodium falciparum.
Autoimmunity
September 2009
The acquisition of protective immunity in malaria is a slow process during which autoantibodies are produced. The present work aimed at studying a possible interference of autoimmune responses on malaria immune protection. This was done by investigating the presence of autoantibodies in the sera of malarious patients, by searching for reactivity of autoantibodies from autoimmune patients against plasmodial antigens, and by studying the effect of such antibodies on the in vitro growth of Plasmodium falciparum.
View Article and Find Full Text PDFTrypanosoma rangeli Tejera, 1920, in chronic Chagas' disease patients under ambulatory care at the Evandro Chagas Clinical Research Institute (IPEC-Fiocruz, Brazil).
Parasitol Res
August 2008
We report the finding, the isolation by hemoculture, and the characterization of Trypanosoma rangeli stocks from two chronic Chagas' disease patients who received ambulatory care at the Evandro Chagas Clinical Research Institute (IPEC, FIOCRUZ). Both patients proceeded from Bahia State (Brazil). One of them presented the cardiac form of the disease and the other indeterminate symptomalogy.
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