Publications by authors named "Maria Asuncion Ballester"
Impact of Biological Agents on Imaging and Biomarkers of Cardiovascular Disease in Patients with Psoriasis: A Systematic Review and Meta-Analysis of Randomized Placebo-Controlled Trials.
Alvaro González-Cantero Daniel Ortega-Quijano Noelia Álvarez-Díaz Maria Asuncion Ballester Natalia Jimenez-Gomez
J Invest Dermatol
October 2021
Article Synopsis
- The study investigates how biologic therapies impact cardiovascular disease risk in psoriasis patients through a systematic review and meta-analysis of placebo-controlled trials.
- Five relevant studies were analyzed, finding no significant reduction in aortic vascular inflammation with adalimumab compared to placebo, although ustekinumab showed some benefit at 12 weeks.
- Results indicate that while TNF-α inhibitors like adalimumab and phototherapy reduce certain blood biomarkers (CRP, IL-6), further research on actual cardiovascular events is necessary to guide clinical decisions.