The role of prophylactic transfusion on the maternal and fetal outcomes in pregnant women with sickle cell disease: A systematic review and meta-analysis.

Background: In the present review, we aimed to synthesize evidence from studies on the safety and effectiveness of prophylactic blood transfusion in pregnant women with sickle cell disease.

Material And Methods: To gather relevant information, we conducted systematic electronic searches of databases such as SCOPUS, Medline via PubMed, Web of Science, and Cochrane Central Register of Controlled Trials. We included both retrospective and prospective studies that examined the impact of prophylactic blood transfusions during pregnancy.

Frequency and Severity of Thrombocytopenia in Neonatal Sepsis.

Background Neonatal sepsis includes numerous systemic illnesses such as septicemia, meningitis, urinary tract infections, and pneumonia. In developing countries, the major reason for neonatal mortality is septicemia, which accounts for almost 50% of overall deaths. Thrombocytopenia is one of the most common hematological problems during the neonatal period, affecting the majority of sufferers admitted to the neonatal intensive care unit (NICU).

Retraction: The Role of Heat Shock Proteins in Cellular Homeostasis and Cell Survival.

[This retracts the article DOI: 10.7759/cureus.18316.

Correction: The Role of Heat Shock Proteins in Cellular Homeostasis and Cell Survival.

[This corrects the article DOI: 10.7759/cureus.18316.

The Role of Heat Shock Proteins in Cellular Homeostasis and Cell Survival.

This review article has been necessitated by the limited number of studies on the role of heat shock proteins (HSPs) in cellular functions. The analysis is performed by reviewing evidence in various literary works concerning the topic. The main function of HSPs is to prevent the formation of non-functional proteins and facilitate protein folding.

Correlation between serum leptin level and Body mass index (BMI) in patients with type 2 diabetes Mellitus.

Objective: To correlate serum leptin levels in obese and non-obese type 2 diabetic patients and compare them with healthy individuals.

Methods: The case-control study was conducted at the Lady Reading Hospital, Peshawar, and the Rehman Medical College, Peshawar, Pakistan, from June to November 2017, and comprised type 2 diabetic patients and and an equal number of healthy controls. Fasting blood glucose, glycated haemoglobin, serum leptin, and body mass index were assessed in obese and non-obese subjects.

Biochemical profile changes in stored donor blood for transfusion.

Objectives: This study's aim was to find out that how various biochemical parameters of donor blood are affected during storage.

Methods: This cross-sectional study was conducted in hematology Unit of Rehman Medical Institute, Peshawar and Fatimid Foundation, Peshawar Khyber Pakhtunkhwa, over a period of six months from June 2018 to November 2018. This study includes 300 healthy volunteer donors.

Frequency of human papilloma virus in patients with oesophageal squamous cell carcinoma in Khyber Pakhtunkhwa.

To determine the frequency of human papilloma virus (HPV) in patients with oesophageal squamous cell carcinoma. A descriptive, cross-sectional method was adopted and the study was conducted in the histopathology department of Rehman Medical Institute, Peshawar, Pakistan, from January to June 2017, and included patients with Oesophageal squamous cell carcinoma. Non-probability consecutive sampling technique was used.

Chronic myeloid leukaemia presenting as priapism: A case report from Khyber Pakhtunkhwa.

Priapism is known as a very rare complication of leukaemia. We report a 16-years boy who presented with the persistent painful erection of the penis for eleven days. He had aspiration without achieving sustained detumescence.

Clinical manifestations of patients with Systemic Lupus Erythematosus (SLE) in Khyber Pakhtunkhwa.

Objective: To determine major symptoms and signs in patients of systemic lupus erythematosus.

Methods: This cross-sectional study was conducted at the Lady Reading Hospital, Khyber Teaching Hospital and Hayatabad Medical Complex, Peshawar, Pakistan, from January 15, 2014, to August 15, 2016, and comprised patients of systemic lupus erythematosus. Data was collected through an interview-based questionnaire containing questions about different symptoms.