Tandem plasmapheresis and hemodialysis: efficacy and safety.

Background: Hemodialysis (HD) and plasmapheresis (PE) are usually performed independently on patients who require renal replacement therapy. We analyzed our experience using a technique that performs both modalities simultaneously.

Methods: Thirty-six patients who were treated with 287 tandem PE and HD (TPH) sessions (mean 7.

Monocytes from dialysis patients exhibit characteristics of senescent cells: does it really mean inflammation?

Hemodialysis treatment induces mononuclear cell activation particularly if cellulosic hemodialysis membrane is used. In normal cells, repeated activation induce a process of accelerate cellular senescence. The aim of the present study was to evaluate whether the mononuclear cell activation associated to hemodialysis with cellulosic membranes favors a process of accelerate senescence in mononuclear cells.

The effects of control of thermal balance on vascular stability in hemodialysis patients: results of the European randomized clinical trial.

Background: Many reports note that the use of cool dialysate has a protective effect on blood pressure during hemodialysis (HD) treatments. However, formal clinical trials in which dialysate temperature is tailored to the body temperature of appropriately selected hypotension-prone patients are lacking.

Methods: We investigated the effect of thermal control of dialysate on hemodynamic stability in hypotension-prone patients selected from 27 centers in nine European countries.