Publications by authors named "Maria Anna Sarno"

Diagnosis of ovarian mass during pregnancy is a rare event. Treatment of ovarian malignancies during pregnancy depends on histology, grade, stage, and gestational weeks. When possible, surgical excision is indicated, and sometimes, fertility-sparing surgery is recommended.

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Background: Breast reconstruction after mastectomy is currently considered an essential component in managing breast cancer patients, particularly those diagnosed at a young age. However, no studies have been published on the feasibility of immediate breast reconstruction in patients diagnosed and operated during the course of gestation.

Method: We retrospectively identified all breast cancer patients who were subjected to mastectomy and immediate breast reconstruction during pregnancy at the European Institute of Oncology between 2002 and 2012.

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Article Synopsis
  • Monoclonal antibodies (mAbs) are important for treating tumors but their safety for pregnant women is unclear.
  • A review of literature from 2000 to 2013 showed limited data on using mAbs during pregnancy, highlighting that bevacizumab may harm fetal development and should be avoided.
  • Trastuzumab is linked to complications like oligohydramnios and poor neonatal outcomes, particularly if used after the first trimester, while rituximab appears to have less risk but may cause temporary low white blood cell counts in newborns.
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An increasing number of women are diagnosed with cancer during pregnancy and lactation. Women are usually advised to interrupt breastfeeding during systemic anticancer treatment for fear of serious adverse effects to the nursed infant. However, the issue is poorly addressed in the literature and very few studies have evaluated the safety of breastfeeding during or after cytotoxic drugs or target agents administration.

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