Publications by authors named "Maria Anna Canciello"
Article Synopsis
- - Lung cancer is the leading cause of cancer-related deaths globally, with poor outcomes for early-stage non-small cell lung cancer (NSCLC) after surgery due to high relapse rates.
- - Immunotherapy is being explored in both neoadjuvant (before surgery) and adjuvant (after surgery) settings to improve survival rates, with drugs like atezolizumab and nivolumab recently approved for these uses.
- - Ongoing research aims to address key questions about the best sequencing and timing of treatments, combination therapies, the use of biomarkers for patient selection, and relevant clinical trial endpoints.
Traditionally, lymph node metastases (LNM) evaluation is essential to the staging of colon cancer patients according to the TNM (tumor-node-metastasis) system. However, in recent years evidence has accumulated regarding the role of emerging pathological features, which could significantly impact the prognosis of colorectal cancer patients. Lymph Node Ratio (LNR) and Log Odds of Positive Lymph Nodes (LODDS) have been shown to predict patients' prognosis more accurately than traditional nodal staging and it has been suggested that their implementation in existing classification could help stratify further patients with overlapping TNM stage.
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