Publications by authors named "Maria Angels Ribas"
Article Synopsis
- The study focused on the impact of SARS-CoV-2 on people living with HIV in the Balearic Islands, specifically examining the incidence and factors contributing to infection and vaccination rates.
- A total of 3,567 HIV patients were analyzed, revealing a 29% SARS-CoV-2 infection rate, with men who have sex with men being at higher risk, while factors like African origin and vaccination coverage were associated with lower risk.
- The findings highlighted that vaccination is crucial for preventing SARS-CoV-2 infection, and revealed that older age and higher comorbidity scores led to increased vaccine uptake.
Introduction: In a previous interim 24-week virological safety analysis of the PROTEST study (1), initiation of Maraviroc (MVC) plus 2 nucleoside reverse-transcriptase inhibitors (NRTIs) in aviremic subjects based on genotypic tropism testing of proviral HIV-1 DNA was associated with low rates of virological failure. Here we present the final 48-week analysis of the study.
Methods: PROTEST was a phase 4, prospective, single-arm clinical trial (ID: NCT01378910) carried on in 24 HIV care centres in Spain.
The number of HIV-infected individuals with prior multiple treatment failures is increasing as time passes by. The success of antiretroviral therapy in these patients is often compromised by the selection of drug-resistant viruses. Despite initial concerns, a rebound in AIDS cases among heavily treatment-experienced patients failing virologically their antiretroviral therapy has not occurred yet.
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