Publications by authors named "Maria Alma Posadinu"
Introduction: Burn injuries pose significant challenges in healthcare, with Integra dermal regeneration template (DRT) emerging as a prominent solution to enhance wound healing and recovery. Although there is no clear consensus on its technical use and application. We convened a panel of 14 burn specialists aiming to provide consensus regarding the application and usage of Integra in managing burn wounds.
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- Nexobrid®, a bromelain-based enzymatic debridement, is increasingly recommended for burn treatment based on expert input from Italian burn centers.* -
- A consensus panel of Italian experts, using the Delphi method, reached almost full agreement on the guidelines for using enzymatic debridement, with 24 out of 27 statements receiving strong consensus.* -
- The resulting recommendations are tailored to the Italian context and will evolve over time with new evidence, enhancing the existing literature on burn surgery practices.*
Purpose: Toxic epidermal necrolysis (TEN) is a rare, life-threatening, drug-induced, mucocutaneous disease, which can severely affect the ocular surface. The purpose of this study was to investigate the efficacy of plasmapheresis, human IV immunoglobulins (IVIg), and autologous serum (AS) eyedrops in the treatment of the severe acute ocular complications of TEN.
Methods: A retrospective chart review of all patients admitted to the Burn Unit, Azienda Ospedaliero-Universitaria-Sassari, Sassari, Italy, from 2009 to 2015, identified 9 patients (2 men, 7 women; mean age 63.
Toxic epidermal necrolysis or Lyell's syndrome is a life-threatening, drug-induced disorder characterized by severe epidermal injury. Although plasmapheresis is expensive and requires easy venous access, it could be included in the first-line treatment of toxic epidermal necrolysis. The method is safe and effective, providing prompt relief from pain and rapid cessation of necrolysis.
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