Compulsory vaccination against COVID-19 in the context of the principles of the convention on human rights and biomedicine.

Introduction: At this stage of the global health crisis caused by the SARS-CoV-2 coronavirus, an increasing number of countries are considering enacting legislation requiring compulsory vaccination or implementing a mechanism to ensure mass vaccination of the population. Such policy decisions raise a number of legal and deontological issues.

Aim: The aim of the study was to analyze the legal and deontological issues related to the introduction of compulsory vaccination against COVID-19 in the context of the principles of the Convention on Human Rights and Biomedicine (Oviedo Convention).

Early neurological and cognitive impairments in subclinical cerebrovascular disease.

Background: The subclinical cerebrovascular disease (SCVD) is an important public health problem with demonstrated prognostic significance for stroke, future cognitive decline, and progression to dementia. The earliest possible detection of the silent presence of SCVD in adults at age at risk with normal functioning is very important for both clinical doctors and scientists.

Materials And Methods: Seventy-seven adult volunteers, recruited during the years 2005-2007, with mean age 58.

Transient ischaemic attacks and minor strokes (analyses and clinically significant comparisons).

Unlabelled: The transient ischaemic attacks (TIA) and minor strokes are independent predictors of disabling strokes with a high medical and social value.

Purpose: Analysis and comparison of the data from the clinical monitoring of TIA and minor stroke patients in correlation with the different duration of the transient neurological deficit.

Patients And Methods: 234 patients were monitored clinically in the Clinic of Cerebrovascular Diseases, University Hospital "St.

Assessment of the effect of palliative radiotherapy for cancer patients with intracranial metastases using EORTC-QOL-C30 questionnaire.

Unlabelled: Assessment of quality of life (QOL) is of crucial importance when assigning palliative radiotherapy of brain metastases in cancer patients.

Aim: To investigate the influence of whole brain radiotherapy on brain symptoms in patients with cerebral metastases; to evaluate their quality of life before and after radiation therapy using the EORTC-QOL-C30 questionnaire, as well as its influence on patients' survival.

Patients And Methods: Sixty-five patients with various locations of the primary tumor and brain metastases were included in this study.

A study of plasma total homocysteine levels in healthy people.

Unlabelled: Elevated plasma levels of homocysteine have been identified as an independent risk factor for atherosclerosis.

Aim: The aim of this study was to determine the reference limits of plasma total homocysteine for Bulgarian population.

Materials And Methods: We investigated 153 healthy individuals without vitamin deficiency aged from 18 to 65 years.

Specific peculiarities in the family model of the Turkish minority in Bulgaria.

Introduction: There is a significant decrease in the average number of children in Bulgarian families during the 80s and 90s. This phenomenon is noticed even in some regions with usually higher natality, like Kurdjali, Pazardjik, Blagoevgrad, etc.

Aim: The aim of this study was to characterize the reproductive behaviour of Turkish minority in Bulgaria.