Cotton cellulose nanofiber/chitosan scaffolds for skin tissue engineering and wound healing applications.

Chitosan (CS) is a promising polymeric biomaterial for use in scaffolds forskin models and wound dressings, owing to its non-antigenic and antimicrobial properties. However, CS often exhibits insufficient physicochemical properties, mechanical strength, and bioactivity, limiting its efficacy in demanding applications. To address these challenges, cotton cellulose nanofibers (CNFs) represent a promising nanomaterial for enhancing CS-based scaffolds in tissue engineering.

Carboxymethylcellulose production from sugarcane bagasse: A new approach in biorefinery concept.

Although the production of carboxymethylcellulose from different raw materials is commercial, its preparation from agro-industrial residues has still been poorly explored in terms of performance, cost-effectiveness, and sustainability. Here, sugarcane bagasse was used as raw material for the carboxymethylcellulose (CMCb) synthesis within the biorefinery context. Sequential treatments were used for the removal of hemicellulose and lignin and the isolation of cellulose, whose conversion into CMCb was carried out through treatments with NaOH and monochloroacetic acid (MCA).

The potential of nanofibrillated cellulose from Hevea brasiliensis to produce films for bio-based packaging.

Cellulose micro/nanofibril (MNFC) films are an interesting alternative to plastic-based films for application in biodegradable packaging. In this study, we aimed to produce and characterize MNFC films obtained from alkaline-pretreated rubberwood (Hevea brasiliensis) waste and Eucalyptus sp. commercial pulp.

Exploring the potential of cellulose autofluorescence for optical detection of tannin in red wines.

The growing demand for opto-electronic devices within an automated landscape has opened up new opportunities for harnessing sustainable cellulose materials for sensors technology. Cellulose, a versatile material, enables its combination with other materials, but in most of these applications, cellulose is typically employed as support or substrate, while its inherent autofluorescence remains largely underexplored for sensors. In light of this context, this study delves into the autofluorescence characteristics of pristine cellulose nanocrystals extracted from wood via enzymatic route for optical sensors tailored to detect tannins.

Cytocompatible and osteoinductive cotton cellulose nanofiber/chitosan nanobiocomposite scaffold for bone tissue engineering.

Natural polymeric nanobiocomposites hold promise in repairing damaged bone tissue in tissue engineering. These materials create an extracellular matrix (ECM)-like microenvironment that induces stem cell differentiation. In this study, we investigated a new cytocompatible nanobiocomposite made from cotton cellulose nanofibers (CNFs) combined with chitosan polymer to induce osteogenic stem cell differentiation.

Mining waste and coconut fibers as an eco-friendly reinforcement for the production of concrete blocks.

Using mineral and agro-industrial wastes associated with the cement matrix can add value and guarantee suitable properties for reinforced composites. This research aimed to evaluate the effect of the incorporation of quartzite and coconut fibers on masonry blocks' physical, mechanical, and thermal properties. Quartzite was evaluated replacing 0%, 25%, 50%, 75%, and 100% of the sand, whereas the coconut fibers were added in a proportion of 2.

Mandacaru cactus as a source of nanofibrillated cellulose for nanopaper production.

In this work, nanofibrillated cellulose (NFC) was extracted from cactus Cereus jamacaru DC. (mandacaru) for nanopaper production. The technique adopted includes alkaline treatment, bleaching, and grinding treatment.

Efferocytosis of SARS-CoV-2-infected dying cells impairs macrophage anti-inflammatory functions and clearance of apoptotic cells.

COVID-19 is a disease of dysfunctional immune responses, but the mechanisms triggering immunopathogenesis are not established. The functional plasticity of macrophages allows this cell type to promote pathogen elimination and inflammation or suppress inflammation and promote tissue remodeling and injury repair. During an infection, the clearance of dead and dying cells, a process named efferocytosis, can modulate the interplay between these contrasting functions.

Eco-friendly laccase and cellulase enzymes pretreatment for optimized production of high content lignin-cellulose nanofibrils.

Lignin-cellulose nanofibrils (LCNF) are of attracting an increasing interest due to the benefits of maintaining the lignin in the nanomaterial composition. The production of LCNF requires considerable energy consumption, which has been suppressed employing pretreatment of biomass, in which it highlights those that employ enzymes that have the advantage of being more environmentally friendly. Some negative aspects of the presence of lignin in the fiber to obtain cellulose nanofibrils is that it can hinder the delamination of the cell wall and act as a physical barrier to the action of cellulase enzymes.

Antifungal and physicochemical properties of Ocimum essential oil loaded in poly(lactic acid) nanofibers.

Poly(lactic acid) (PLA) nanofibres containing different proportions of the essential oils from Ocimum basilicum L. and Ocimum gratissimum L. were prepared by solution blow spinning method.

Bio-based films/nanopapers from lignocellulosic wastes for production of added-value micro-/nanomaterials.

The growing demand for products with lower environmental impact and the extensive applicability of cellulose nanofibrils (CNFs) have received attention due to their attractive properties. In this study, bio-based films/nanopapers were produced with CNFs from banana tree pseudostem (BTPT) wastes and Eucalyptus kraft cellulose (EKC) and were evaluated by their properties, such as mechanical strength, biodegradability, and light transmittance. The CNFs were produced by mechanical fibrillation (after 20 and 40 passages) from suspensions of BTPT (alkaline pre-treated) and EKC.

Infection of human lymphomononuclear cells by SARS-CoV-2.

Although SARS-CoV-2 severe infection is associated with a hyperinflammatory state, lymphopenia is an immunological hallmark, and correlates with poor prognosis in COVID-19. However, it remains unknown if circulating human lymphocytes and monocytes are susceptible to SARS-CoV-2 infection. In this study, SARS-CoV-2 infection of human peripheral blood mononuclear cells (PBMCs) was investigated both and .

Genetic diversity associated with natural rubber quality in elite genotypes of the rubber tree.

The objective of this study was to evaluate the genetic variability of natural rubber latex traits among 44 elite genotypes of the rubber tree [Hevea brasiliensis (Willd. ex Adr. de Juss.

Active coatings of thermoplastic starch and chitosan with alpha-tocopherol/bentonite for special green coffee beans.

The quality of green coffee beans (GCBs) is possibly affected by storage conditions. Edible polymer coatings for GCBs can help preserve flavors and improve shelf life of GCBs. This study aimed to incorporate α-tocopherol, a powerful antioxidant, in thermoplastic starch [TPS] and chitosan [TPC] and determined the best cavitation energy (960-3840 J·mL) using an ultrasonic probe.

Preparation, Characterization and Biocompatibility Studies of Cotton Cellulose Nanofibers.

Cellulose nanofibers have mechanical properties that make them very attractive in a myriad of fields such as biomedicine, tissue engineering, biosensors, cosmetics and food packet products. To evaluate the potential health risks of airborne cellulose nanofibers, the cellulose nanofiber was prepared and characterized and then its pulmonary potential toxicity to a mouse model was studied. Cellulose nanofiber has been prepared by acid hydrolysis of cotton cellulose and characterized by transmission electron microscopy, zeta potential and X-ray diffraction analysis.

Enhancement of the Amazonian Açaí Waste Fibers through Variations of Alkali Pretreatment Parameters.

The açaí fruit depulping produces large amounts of long lignocellulosic fiber bundles that are disposed in the environment. Chemical pretreatments may improve açaí fibers favoring their usage in advanced materials. This work aimed to define optimal alkali reaction parameters to improve the properties of açaí fibers.

Study of morphological properties and rheological parameters of cellulose nanofibrils of cocoa shell (Theobroma cacao L.).

Cocoa shell was evaluated as a precursor for cellulose nanofibrils (NFCs) using mechanical defibrillation. Its morphology was analysed using optical microscopy and scanning electron microscopy with field emission. Rheological and mechanical behaviour were evaluated through flow curves with a strain rate ranging from 0 to 300 s at 25 °C and by means of oscillatory frequency sweeps (0.

Hydrophobic edible films made up of tomato cutin and pectin.

Cutin is the biopolyester that protects the extracellular layer of terrestrial plants against dehydration and environmental stresses. In this work, cutin was extracted from tomato processing waste and cast into edible films having pectin as a binding agent. The influences of cutin/pectin ratio (50/50 and 25/75), film-forming suspension pH, and casting method on phase dispersion, water resistance and affinity, and thermal and mechanical properties of films were investigated.

Chemical treatment and characterization of soybean straw and soybean protein isolate/straw composite films.

This work investigated changes in the chemical composition and structure of soybean straw (SS) treated with alkali (NaOH 5% and 17.5%) and bleached with hydrogen peroxide (HO) or sodium hypochlorite (NaOCl). Removal of the amorphous constituents increased the degree of crystallinity and the content of cellulose fibers particularly after reaction with high concentrations of alkali.

Atrial fibrillation in women: treatment.

Sex-specific differences in the epidemiology, pathophysiology, presentation, prognosis, and treatment of atrial fibrillation (AF) are increasingly recognized. Women with AF generally experience worse symptoms, poorer quality of life, and have higher risk of stroke and death than men with AF. Effective treatment of the arrhythmia in women is critical to reduce the rate of adverse events.

Postmarketing Safety Events Relating to New Drugs Approved in Brazil Between 2003 and 2013: A Retrospective Cohort Study.

This study investigated postmarketing safety events (PMSEs) for new drugs approved in Brazil and evaluated whether a range of drug characteristics influenced the time between approval and the first PMSE. This retrospective study included new drugs registered between 2003 and 2013 by the National Health Surveillance Agency (ANVISA), which is responsible for medicines approval in Brazil. PMSEs were defined as any drug safety alert or drug withdrawal from the market.

Assessment of psychometric properties of the Brazilian version of the oral anticoagulation knowledge test.

Background: The aim of this study was to evaluate the psychometric properties of the Brazilian version of the Oral Anticoagulation Knowledge (OAK) Test.

Methods: This study, conducted in an anticoagulation clinic, included 201 Brazilian participants aged over 18 years, who had been using warfarin for more than two months. The reliability of the instrument was evaluated by assessing internal consistency (Kuder-Richardson coefficient) and reproducibility (test-retest reliability).

Consumption of medicinal plants by patients with heart diseases at a pharmacist-managed anticoagulation clinic in Brazil.

Background: Medicinal plants (MP) have been used for many years with the purpose of feeding and curing. Several MP may interfere in drug response and are not always considered as potential drug-interactors in clinical practice.

Objective: To investigate the consumption of MP by outpatients during a one-year follow-up.

Drug-Induced Nephrotoxicity and Dose Adjustment Recommendations: Agreement Among Four Drug Information Sources.

: Hospitalized patients require the use of a variety of drugs, many of which individually or in combination have the potential to cause kidney damage. The use of potentially nephrotoxic drugs is often unavoidable, and the need for dose adjustment should be evaluated. This study is aimed at assessing concordance in information on drug-induced nephrotoxicity and dose adjustment recommendations by comparing four drug information sources (DRUGDEX(®), UpToDate(®), Medscape(®) and the Brazilian Therapeutic Formulary) using the formulary of a Brazilian public hospital.

Prescribing errors in antibiotic prophylaxis by dentists in a large Brazilian city.

Prescribing errors may contribute to antibiotic resistance and other drug-related problems. To investigate the quality of prescriptions involving antibiotic prophylaxis by dentists in a large Brazilian city, 366 dental prescriptions were randomly selected from 31,105. A prophylaxis indication represented 24.