Publications by authors named "Maria A Fiol"
Growth hormone (GH) and melatonin are two hormones with quite different physiological effects. Curiously, their secretion shows parallel and severe age-related reductions. This has promoted many reports for studying the therapeutic supplementation of both hormones in an attempt to avoid or delay the physical, physiological, and psychological decay observed in aged humans and in experimental animals.
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- * Experiments on old rats showed that chronic melatonin administration (1 mg/kg/day for 4 weeks) significantly reversed age-related deficits in key neurotransmitters—serotonin, dopamine, and norepinephrine—and improved behavioral performances.
- * Both melatonin and its precursor L-tryptophan enhanced monoamine synthesis, suggesting a long-term positive impact on cognitive functions and motor coordination in aging individuals.