The in vitro motility assay parameters of actin filaments from Mytilus edulis exposed in vivo to copper ions.

One important aspect of oxidative stress is chemical modification of lipids, proteins and nucleic acids. Copper has been shown to be one of the agents causing oxidative stress. In muscles copper binds to Cys-374 of the actin monomer and catalyzes interchain S-S bond formation in F-actin.