Publications by authors named "Maria A Basile"

Background: There are limited comprehensive descriptions of character strengths and virtues specific to the professional identity formation of medical students in the literature. This absence of a satisfactory summation of virtues has stimulated us to attempt a conceptual framework utilizing a tripartite taxonomy. This taxonomy reflects recent interest in and importance of justice and care of the self.

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In the present work, microporous membranes based on poly(ε-caprolactone) (PCL) and PCL functionalized with amine (PCL-DMAEA) or anhydride groups (PCL-MAGMA) were realized by solvent-non solvent phase inversion and proposed for use in Guided Tissue Regeneration (GTR). Nanowhiskers of hydroxyapatite (HA) were also incorporated in the polymer matrix to realize nanocomposite membranes. Scanning Electron Microscopy (SEM) showed improved interfacial adhesion with HA for functionalized polymers, and highlighted substantial differences in the porosity.

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Objectives: The aim of this study was to analyze the features of an oxidized titanium implant surface and to evaluate its effects on the response of human gingival fibroblasts.

Methods: 10mm×10mm×1mm turned (control) and oxidized (test) titanium samples (P.H.

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Purpose: In the framework of a project aiming to improve the properties of poly(ε-caprolactone) (PCL)-based devices, we prepared novel composites and tested their in vitro biocompatibility and osteogenic capacity on human mesenchymal stromal cells (MSC) from bone marrow.

Methods: We prepared two functionalized derivatives, PCL-g-MAGMA and PCL-g-DMAEA, by insertion of anhydride groups by radical grafting of maleic anhydride (MA) and glycidyl-methacrylate (GMA) molecules, and by insertion of N-(dimethylamino)ethylacrylate (DMAEA) of tertiary amines groups, respectively. In addition, in order to improve the osteoconductive properties of the materials, we also prepared the corresponding composites containing the mineral component of bone, namely hydroxyapatite (HA).

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Background: The introduction of specific BCR-ABL inhibitors in chronic myelogenous leukemia therapy has entirely mutated the prognosis of this hematologic cancer from being a fatal disorder to becoming a chronic disease. Due to the probable long lasting treatment with tyrosine-kinase inhibitors (TKIs), the knowledge of their effects on normal cells is of pivotal importance.

Design And Methods: We investigated the effects of dasatinib treatment on human bone marrow-derived mesenchymal stromal cells (MSCs).

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Objectives: Titanium nitride (TiN) coating has been proposed as an adjunctive surface treatment aimed to increase the physico-mechanical and aesthetic properties of dental implants. In this study we investigated the surface characteristics of TiN-coated titanium plasma sprayed (TiN-TPS) and uncoated titanium plasma sprayed (TPS) surfaces and their biological features towards both primary human bone marrow mesenchymal stem cells (BM-MSC) and bacterial cultures.

Methods: 15 mm×1 mm TPS and TiN-TPS disks (P.

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Article Synopsis
  • The study explored how different immobilizing hydrogels impact biohydrogen production by a Thermoanaerobacterium isolate, finding that immobilization enhances both substrate conversion and hydrogen production.
  • Using alginate-supported cultures resulted in a hydrogen yield of 1.9 mol H(2)/mol glucose after 24 hours, while cationic acrylic hydrogels boosted cell immobilization and achieved a peak production of 3.6 mol H(2)/mol glucose.
  • Despite good durability of all tested hydrogels in repeated batch runs, the buildup of gaseous and acidic byproducts hindered continued hydrogen production, redirecting carbon flow towards other metabolites and biomass.
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