Intergenerational inheritance induced by a high-fat diet causes hyperphagia and reduced hypothalamic sensitivity to insulin and leptin in the second-generation of rats.

Objective: The aim was to investigate the intergenerational inheritance induced by a high-fat diet on sensitivity to insulin and leptin in the hypothalamic control of satiety in second-generation offspring, which were fed a control diet.

Methods: Progenitor rats were fed a high-fat or a control diet for 59 d until weaning. The first-generation and second-generation offspring were fed the control diet until 90 d of age.

Environmental and behavioral factors associated with household transmission of SARS-CoV-2 in children and adolescents.

Objective: To analyze the association between risk behaviors and environmental factors and SARS-CoV-2 infection in children and adolescents in the family environment.

Methods: Cross-sectional study. A total of 267 children and adolescents aged 5-19 years who have contact with COVID-19-positive essential workers were tested between June and October 2020.

Judicialization and cancer: quality of life of patients and caregivers in the COVID-19 pandemic.

Background: In Brazil, cancer patients and caregivers of cancer patients seek judicial intervention for free access to medications from the public health system. Indeed, the COVID-19 pandemic potentially affected the health-related quality of life of cancer patients and caregivers of cancer patients. This study aimed to describe the sociodemographic profile and assess the health-related quality of life of patients and caregivers in the state of Goias, Brazil, in 2020.

Health literacy of people with spinal cord injury: a systematic review.

Study Design: Systematic review.

Objective: To systematically review the evidence on health literacy (HL) of people diagnosed with spinal cord injury (SCI).

Methods: PubMed, Cochrane Library, Web of Science and Embase databases were used to identify studies published from 1974 to 2021.

First report of causing grape ripe rot in Brazil.

cv. BRS Vitória is a seedless black table grape cultivar with an extremely pleasant flavor and is adapted to cultivation in all Brazilian regions. Between November and December 2021, grape berries presenting typical ripe rot symptoms were found in three vineyards located in Petrolina, Pernambuco Brazil.

Tangency and multiple factors of violence against lecturer: nuances of the experience in pedagogical practices in health education.

Objective: to identify factors that lead the teacher to experience violence in their pedagogical practice in health education.

Method: research with a qualitative approach, based on the Grounded Theory, conducted with 11 professors of the nursing course of a public university in the central region of Brazil in 2020 and 2021. Online semi-structured interviews were analyzed partially in the light of the Constructivist Grounded Theory.

Access and Use of Health Services by People with Diabetes from the Item Response Theory.

The objective of this study was to analyze the indicators of access and use of health services in people with diabetes mellitus. This study used data from the National Health Survey, conducted in Brazil in 2013. The National Health Survey was carried out with adults aged 18 years or older residing in permanent private households in Brazil.

Reproductive Desire in Women Living with HIV/AIDS with Serodiscordant Partners.

Objective: To estimate the prevalence and factors associated with reproductive desire in a sample of women living with HIV/AIDS (WLHA) with serodiscordant partners.

Study Design: Between September 2015 and August 2016, a cross-sectional study was conducted among 110 WLHA from HIV/AIDS treatment services and non-governmental organizations. An interview was conducted using a structured questionnaire to collect sociodemographic data, reproductive desire, and potential predictor variables.

Instruments to assess the role of the clinical pharmacist: a systematic review.

Background: The clinical pharmacist is an essential member of the healthcare team and plays an important role in health care in the primary care and the hospital setting. Knowledge regarding the instruments that evaluate the different activities of the clinical pharmacist, as well as the evaluation of the psychometric properties of these instruments, is necessary.

Methods: A literature search was performed in the PubMed and Scopus electronic databases without time and language restrictions.

Judicialization of health: profile of demands for oncological medicines in a state in the central region of Brazil.

Background: The significant increase in access to oncological medicines through court cases suggests that constitutional guarantees of integral and universal care in the Brazilian public health system are uncertain.

Methods: A retrospective observational study was conducted to analyze data from lawsuits requesting oncological medicines from 2014 to 2020 in the State of Goiás, Brazil, in state and federal courts. Sociodemographic, medical, and legal variables were statistically examined using descriptive, association, and correlation methods.

Progenitor with cardiometabolic disorders increases food intake, systemic inflammation and gut microbiota alterations in the second-generation offspring.

This work presents the effects of the high-fat diet (H) consumed by the progenitor (G) on cardiometabolic disorders and intestinal microbiota in the second-generation offspring (F). The rats submitted to H (GH) or control (C) (GC) diets, during mating, gestation and lactation, generated F offspring (F-GH and F-GC, respectively), which received only the C diet. Both, GH and F-GH, showed changes in the intestinal microbiota, increased MAP, plasma TAG levels, adiposity index and the inflammatory process in retroperitoneal fat and in the colon shown by increased TNF-α, MCP-1, MyD88 and CAV-1 gene expression.

Competencies of health personnel for the practice of health literacy in Brazil: A Delphi consensus survey.

Objective: The aim of this study was to identify a set of competencies of health personnel for the practice of health literacy in Brazil.

Methods: Scoping review and online interviews with healthcare practitioners, followed by three rounds of the modified e-Delphi method with health literacy specialists from November/2020 to March/2021. During the rounds, the items were revised, new items added for review, and their importance was rated on a five-point Likert scale in an online form.

Professional Responsiveness to Health Literacy: A Scoping Review.

Background: Difficulty in understanding and using health information can harm the patient and increase the cost of care provided. So, this study classified and mapped the characteristics and interventions that make health care professionals responsive to the patient's health literacy.

Methods: Medline (PubMed), CINAHL (EBSCO), PsycInfo, ERIC (ProQuest), Lilacs (BVS) and EMBASE (Elsevier) were searched using a combination of controlled descriptors.

[Dimensions of student violence against the teacher].

Violence against teachers is a global concern and has a negative impact on the development of society. In this context, this study aimed to review definitions of violence against teachers to develop an integrated consensus and conceptual model. A scoping review of the literature was carried out to include articles that could answer the guiding question of the study: "What are the definitions and dimensions of student violence against teachers in teaching?" The studies included in the review, it was identified that violence against the teacher can be defined as a set of actions and situations caused by students in an insidious or chronic way in the workplace and/or through digital medium, mediated by the perception of violence, the copping mechanism of the teacher and the organizational management of the violence.

Driving and restrictive factors of group practice in community psychosocial care services.

This qualitative research aimed to investigate workers' theoretical conceptions regarding group work and analyze the driving and restrictive factors of group therapeutic practice in Psychosocial Care Centers (CAPS). Sixty-six workers from CAPS and outpatient clinics from the Psychosocial Care Network from twenty-three municipalities in the State of Goiás participated in the study. Data were collected through a structured questionnaire and a group interview audio-recorded and documented with photographs.

Caregivers of Individuals with Cancer in the COVID-19 Pandemic: A Phenomenological Study.

Caregivers of individuals with cancer in the COVID-19 pandemic are faced with the demands of cancer and the health needs produced by it, along with their own health and self-care needs, and the uncertainties of expectations and risks. A qualitative analytical phenomenological study with caregivers of individuals with cancer registered at the state referral hospital supplying medications, who answered the sociodemographic assessment questionnaires and semi-structured questions about their feelings and perceptions in the COVID-19 pandemic. Bardin's content analysis was used, with methodological quality assessed using SRQR Standards for Reporting Qualitative Research and the MAXQDA software.

Pain in Hemodialysis Patients: Prevalence, Intensity, Location, and Functional Interference in Daily Activities.

Although pain is a frequent complaint of patients with chronic kidney disease who undergo hemodialysis, few studies have assessed the functional interference of pain in activities of daily living (ADLs). Hence, the aim of this study was to evaluate the prevalence, location, intensity, and functional interference of pain in ADLs of chronic kidney disease patients undergoing hemodialysis and to estimate the association of specific pain sites with severe functional interference by pain in ADLs. This cross-sectional study included patients with chronic kidney disease undergoing hemodialysis.

Association between spirituality/religiousness and quality of life among healthy adults: a systematic review.

Background: Health-related quality of life (HRQoL) is determined by multiple factors that include components such as spirituality and religiousness (S/R). Even though various systematic reviews have investigated the association between S/R and improved health outcomes in the most different groups, healthy young individuals are seldom addressed.

Objective: To assess the association between S/R and HRQoL among young, healthy individuals.

Prevalence of comorbid substance use disorders with anxiety disorders or post-traumatic stress disorder in people seeking treatment for substance abuse: a systematic review protocol.

Objective: This systematic review will aim to assess evidence of the prevalence of comorbid substance use disorders with anxiety disorders or post-traumatic stress disorder in people seeking treatment for substance use.

Introduction: Research shows that anxiety disorders and post-traumatic stress disorder are highly prevalent in people with substance use disorders and can worsen the treatment outcomes, increasing the risk of relapse and poor adherence. However, evidence from systematic reviews on the prevalence of these comorbidities in substance use treatment settings is limited.

Parental stress around ophthalmological health conditions: a systematic review of literature protocol.

Background: Parents can be psychologically impacted when their children are diagnosed with eye diseases, such as blindness, strabismus, and eye cancer. Stress can reduce the quality of parental care and may be linked to the deterioration of parents' and children's mental and physical health and family dynamics. No systematic literature review on parental stress in ophthalmology has been found to provide evidence synthesis capable of stimulating and defining new studies and thereby promoting research in this field.

Quality of life of master's and doctoral students in health.

Objectives: to assess the quality of life of master's and doctoral students in health.

Methods: this is a cross-sectional study carried out with 503 master's and doctoral students from the Brazilian Center-West, using the WHOQOL-BREF to analyze their quality of life. Analysis included Cronbach's alpha coefficient, confirmatory factor analysis and bivariate and multivariate analyzes.

Pain in Patients With Chronic Kidney Disease Undergoing Hemodialysis: A Systematic Review.

Aims: To assess the presence of pain, its location, intensity, and effects on the daily activities of patients with chronic kidney disease (CKD) undergoing hemodialysis (HD).

Participants/subjects: Patients with chronic kidney disease (CKD) undergoing hemodialysis (HD).

Design: A systematic review.

The use of narrative research for the learning of group dynamics by professionals from Psychosocial Care Centers.

Objective: To analyze the results of the use of narratives in group therapy for the qualification process of professionals in the Psychosocial Care Centers on the use of group dynamics.

Method: This is an action research involving 21 workers from 11 Psychosocial Care Centers in the Brazilian Central-West region. For data collection, narratives written by the participants about their work practices with therapeutic groups and theoretical discussion based on in-person workshops were used.

Factors associated with quality of life of older adults with chronic pain.

Objective: To analyze the factors associated with quality of life of the older adults with chronic pain.

Method: Cross-sectional study conducted with 239 older adults in outpatient care in the state of Goiás, Brazil. The World Health Organization Quality of Life-Old (WHOQOL-OLD) instrument contains six domains and was applied to assess quality of life.