Sedative and cardiorespiratory effects of intranasal atomized alfaxalone in Japanese White rabbits.

Objective: To investigate the sedative and cardiorespiratory effects of intranasal atomization (INA) of alfaxalone using a mucosal atomization device in Japanese White rabbits.

Study Design: Randomized, prospective, crossover study.

Animals: A total of eight healthy female rabbits, weighing 3.

Biosynthesis of Poly(3-hydroxybutyrate--3-hydroxyhexanoate) From Glucose by Through Butyryl-CoA Formation Driven by Ccr-Emd Combination.

Poly[()-3-hydroxybutyrate--()-3-hydroxyhexanoate] [P(3HB--3HHx)] is a practical kind of bacterial polyhydroxyalkanoates (PHAs). A previous study has established an artificial pathway for the biosynthesis of P(3HB--3HHx) from structurally unrelated sugars in , in which crotonyl-CoA carboxylase/reductase (Ccr) and ethylmalonyl-CoA decarboxylase (Emd) are a key combination for generation of butyryl-CoA and the following chain elongation. This study focused on the installation of the artificial pathway into .

Feasibility and Usefulness of a Joystick-Guided Robotic Scope Holder (Soloassist) in Laparoscopic Surgery.

Introduction: The Soloassist® system is a joystick-guided robotic scope holder. We evaluated the efficacy of Soloassist in laparoscopic surgery.

Methods: We investigated operative time, blood loss, set-up time, length of hospital stay, and the number of participating surgeons in laparoscopic cholecystectomy cases before and after the introduction of Soloassist.

Maternal ghrelin plays an important role in rat fetal development during pregnancy.

Ghrelin, an acylated peptide serving as an endogenous ligand for GH secretagogue receptor (GHS-R), was originally isolated from rat and human stomach. In this study, we report the critical role of maternal ghrelin in fetal development. High levels of ghrelin receptor (GHS-R) mRNA were detected in various peripheral fetal tissues beginning at embryonic d 14 and lasting until birth.