Publications by authors named "Mari Nakabou"

Aim: Fish oil is associated with decreased arteriosclerosis, cardiovascular disease and the prevention of cellular aging. Most studies of n-3 PUFA (polyunsaturated fatty acid) have been conducted in patients under 80 years of age, and there are few studies of subjects ≥80 years of age. This study investigated the relationship between eicosapentaenoic acid (EPA) or arachidonic acid (AA) and arteriosclerosis in elderly patients ≥80 years of age.

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We herein report two cases of patients with chronic kidney disease who developed hypertensive encephalopathy, which occurred after a sudden discontinuance of antihypertensive agents. Both patients underwent care at our hospital after experiencing neurological abnormalities. In both patients, magnetic resonance imaging (MRI) revealed edema in the cerebral white matter and cortices, basal ganglia, brainstem, and cerebellum.

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Article Synopsis
  • The study investigates the effects of switching from lipophilic simvastatin to hydrophilic pravastatin on serum adiponectin levels in dyslipidemic patients with mild hypertension.
  • Results showed that while low-density lipoprotein cholesterol and blood pressure remained largely unchanged, serum adiponectin significantly increased and C-reactive protein decreased after the switch.
  • The findings suggest that hydrophilic pravastatin may have beneficial effects on adiponectin and inflammation, but further research is needed to understand the reasons behind these differences beyond just the lipophilicity of the statins.
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