Affected brother as the highest risk factor of type 1 diabetes development in children and adolescents: One center data before implementing type 1 diabetes national screening.

Background: There is an increased risk for childhood type 1 diabetes (T1D) when T1D and type 2 diabetes (T2D) are reported in relatives.

Objectives: Our objective was to evaluate current family risk factors for T1D development before implementing a national screening program for T1D.

Material And Methods: A population of 879 Caucasian children and adolescents with T1D and 286 healthy controls were enrolled in the study.