Publications by authors named "Mari Kurokawa"
A 6-year-old boy was diagnosed with chromosomal abnormalities (48,XYY, + 21[11]/46,XY[19]) at 4 months of age after a physical examination revealed an undescended testis and a dwarf penis. He also had mild renal dysfunction and severe proteinuria, and kidney biopsy at 2 years of age revealed focal segmental glomerulosclerosis. Genetic analysis to investigate suspected WT1 gene abnormalities revealed a novel variant in NM_024426.
View Article and Find Full Text PDFBackground: Microorganisms that activate plant immune responses are useful for application as biocontrol agents in agriculture to minimize crop losses. The present study was conducted to identify and characterize plant immunity-activating microorganisms in Brassicaceae plants.
Results: A total of 25 bacterial strains were isolated from the interior of a Brassicaceae plant, Raphanus sativus var.
Background: Henoch-Schönlein purpura nephritis often resolves spontaneously, without treatment, making decisions regarding therapeutic interventions difficult.
Methods: Fifty-four patients who were diagnosed as having Henoch-Schönlein purpura nephritis between April 2004 and March 2018, and developed hematuria and/or proteinuria, were studied retrospectively. The observation period ended at the disappearance of hematuria or proteinuria, or the last observation date before December 2019 for each patient.
Objectives: In children with a first Escherichia coli-induced febrile urinary tract infection (fUTI), routine voiding cytourethrography (VCUG) is not recommended for detecting vesicoureteral reflux (VUR). Meanwhile, the sensitivity of renal and bladder ultrasound (RBUS) for detecting VUR is insufficient. Aiming to implement VCUG properly for children with a first E.
View Article and Find Full Text PDFArticle Synopsis
- This study investigates how maternal chronic diseases affect the likelihood of congenital anomalies of the kidney and urinary tract (CAKUT) in children, differentiating between isolated and complicated cases.
- Conducted through a prospective birth cohort in Japan with over 100,000 children, it identifies specific maternal health conditions, like kidney disease and diabetes, that significantly increase the risks of these anomalies in offspring.
- The research results indicate a 0.6% prevalence of CAKUT, with notable increased risks linked to maternal kidney disease, cancer, and diabetes, although the study faced limitations regarding clinical definitions and criteria.
Microorganisms that activate plant immune responses have attracted considerable attention as potential biocontrol agents in agriculture because they could reduce agrochemical use. However, conventional methods to screen for such microorganisms using whole plants and pathogens are generally laborious and time consuming. Here, we describe a general strategy using cultured plant cells to identify microorganisms that activate plant defense responses based on plant-microbe interactions.
View Article and Find Full Text PDFTranslation and Psychometric Analysis of the Japanese Version of the Perceived Maternal Parenting Self-Efficacy Scale.
J Obstet Gynecol Neonatal Nurs
March 2021
Objective: To translate the Perceived Maternal Parenting Self-Efficacy (PMP S-E) scale to Japanese and test its psychometric properties among Japanese mothers of low-birth-weight (LBW) infants.
Design: Descriptive psychometric study.
Setting: NICUs in two regional perinatal care centers in the Kinki region of Japan.
Background: Acute kidney injury (AKI) often occurs in pediatric patients who received allogeneic hematopoietic cell transplantation (HCT). We evaluated the risk and effect of HCT-related AKI in pediatric patients.
Methods: We retrospectively studied the survival and renal outcome of 69 children 100 days and 1-year posttransplant in our institution in 2004-2016.
Background: Pierson syndrome (PS) is a rare autosomal recessive disorder, characterized by congenital nephrotic syndrome and microcoria. Advances in renal replacement therapies have extended the lifespan of patients, whereas the full clinical spectrum of PS in infancy and beyond remains elusive.
Case Presentation: We present the case of a 12-month-old boy with PS, manifesting as the bilateral microcoria and congenital nephrotic syndrome.
Article Synopsis
- - Hypokalemic periodic paralysis (HypoPP) is an inherited disorder causing temporary muscle weakness and low potassium levels, often linked to mutations in the CACNA1S gene that affects calcium channels.
- - A Japanese woman with HypoPP developed symptoms at age 6, exacerbated by high-carbohydrate diets; her children also began showing similar symptoms at young ages, and testing revealed a specific mutation in all three.
- - Treatment with voglibose and acetazolamide helped manage her paralytic episodes, and the study suggests that the p.V876E mutation in CACNA1S is associated with both early onset and atypical manifestations of HypoPP.