Publications by authors named "Mari Hoya"

Streptococcal toxic shock syndrome (STSS) is a life-threatening illness mainly caused by invasive group A (GAS) infection. Herein, we report a case of a postmenopausal woman who developed STSS from an ascending vaginal GAS infection after cytocervical sampling. The patient complained of vaginal discharge, for which she underwent gynecological examination with vaginal sampling.

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Uterine torsion is extremely rare in postmenopausal women. Total ischemia of the uterus may cause life-threatening conditions; hence, accurate diagnosis and surgical intervention are crucial. However, preoperative diagnosis is often challenging due to nonspecific clinical features and laboratory findings.

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Objective: Tokishakuyakusan (TSS) is a traditional herbal medicine that has been used empirically to prevent recurrent pregnancy loss. Its mode of action remains unclear. With their potent capacity to produce cytokines, invariant natural killer (iNKT) cells are involved in the control of fetomaternal immunity in early gestation.

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Article Synopsis
  • - The study examined how different types of iNKT cell stimulants, specifically Th1-biased AGC and Th2-biased OCH, affect pregnancy outcomes in mice.
  • - Administering OCH led to no pregnancy loss, while AGC resulted in significant fetal loss, with increased serum levels of IL-4 and IL-10 linked to OCH and a spike in IFN-γ associated with AGC.
  • - The findings suggest that regulating Th1/Th2 balance through iNKT cells is crucial for maintaining healthy pregnancies, with IL-4 showing potential to counteract AGC-induced fetal loss.
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Inflammatory cytokines play a major role in spontaneous preterm birth. Resveratrol has strong anti-inflammatory effects, but its effect on preterm birth in vivo is unknown. We investigated whether resveratrol protects against preterm birth in the lipopolysaccharide (LPS)-induced preterm mouse model.

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Interstitial pneumonitis after treatment with pegylated liposomal doxorubicin (PLD) has been rarely reported. We describe herein a case of interstitial pneumonitis in a 49-year-old woman with relapsed ovarian carcinoma treated with PLD. Twenty-five days after the second administration of PLD, she presented with fever and dry cough, and chest CT scans revealed bilateral interstitial infiltrates and ground-glass opacities.

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