Publications by authors named "Margriet J van Gendt"

Intracochlear electrocochleography (ECochG) is a potential tool for the assessment of residual hearing in cochlear implant users during implantation and acoustical tuning postoperatively. It is, however, unclear how these ECochG recordings from different locations in the cochlea depend on the stimulus parameters, cochlear morphology, implant design, or hair cell degeneration. In this paper, a model is presented that simulates intracochlear ECochG recordings by combining two existing models, namely a peripheral one that simulates hair cell activation and a three-dimensional (3D) volume-conduction model of the current spread in the cochlea.

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Objectives: The electrically evoked compound action potential (eCAP) is widely used in the clinic as an objective measure to assess cochlear implant functionality. During the past decade, there has been increasing interest in applying eCAPs for fitting of cochlear implants. Several studies have shown that eCAP-based fitting can potentially replace time-consuming behavioral fitting procedures, especially in young children.

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Article Synopsis
  • The text includes a collection of research topics related to neural circuits, mental disorders, and computational models in neuroscience.
  • It features various studies examining the functional advantages of neural heterogeneity, propagation waves in the visual cortex, and dendritic mechanisms crucial for precise neuronal functioning.
  • The research covers a range of applications, from understanding complex brain rhythms to modeling auditory processing and investigating the effects of neural regulation on behavior.
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Tinnitus is a phantom sound percept that can be severely disabling. Its pathophysiology is poorly understood, partly due to the inability to objectively measure neural correlates of tinnitus. Gaze-evoked tinnitus (GET) is a rare form of tinnitus that may arise after vestibular schwannoma removal.

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