Microalbuminuria, preeclampsia, and preterm delivery in pregnant women with type 1 diabetes: results from a nationwide Danish study.

Objective: To study the association between microalbuminuria and development of preeclampsia and preterm delivery in pregnant women with type 1 diabetes.

Research Design And Methods: This was a population-based prospective study in 846 normoalbuminuric or microalbuminuric women with type 1 diabetes without antihypertensive treatment in early pregnancy. Data were collected prospectively by one to three caregivers in each center and reported to a central registry.

Peri-conceptional A1C and risk of serious adverse pregnancy outcome in 933 women with type 1 diabetes.

Objective: To study the association between peri-conceptional A1C and serious adverse pregnancy outcome (congenital malformations and perinatal mortality).

Research Design And Methods: Prospective data were collected in 933 singleton pregnancies complicated by type 1 diabetes.

Results: The risk of serious adverse outcome at different A1C levels was compared with the background population.

Outcomes in type 1 diabetic pregnancies: a nationwide, population-based study.

Objective: The aim of this study was to compare pregnancy outcomes in type 1 diabetic pregnancies with the background population.

Research Design And Methods: This nationwide prospective multicenter study took place in eight Danish centers treating pregnant women with type 1 diabetes during 1993-1999. A total of 990 women with 1,218 pregnancies and delivery after 24 weeks (n=1,215) or early termination due to severe congenital malformations (n=3) were included.