Publications by authors named "Margret Sigurdadottir"
Article Synopsis
- The significance of tumor-infiltrating lymphocytes (TILs) in diffuse large B-cell lymphoma (DLBCL) is still debated, specifically regarding the impact of regulatory T cells (T(regs)) on patient survival.
- A study analyzing 195 DLBCL patients found that those with fewer cytotoxic T-cells (TIA-1+ cells) had better progression-free survival (PFS) and overall survival (OS) compared to those with more cytotoxic cells.
- In contrast, the presence of regulatory T cells (FOXP3+ cells) did not show any correlation with PFS or OS, suggesting they may have less clinical significance in DLBCL, warranting further investigation.
