Associations between dietary intake of choline and betaine and lung cancer risk.

Evidence from human and animal research indicates that choline metabolic pathways may be activated during a variety of diseases, including cancer. We report results of a case-control study of 2821 lung cancer cases and 2923 controls that assessed associations of choline and betaine dietary intakes with lung cancer. Using multivariable logistic regression analyses, we report a significant association between higher betaine intake and lower lung cancer risk that varied by smoking status.

The association of family history of liver cancer with hepatocellular carcinoma: a case-control study in the United States.

Background/aims: The study aimed at addressing the connection between positive family history of liver cancer and hepatocellular carcinoma (HCC) development in the USA.

Methods: At The University of Texas M.D.