Measurement equivalence of the Marijuana Effect Expectancies Questionnaire-Brief across sex, race/ethnicity, and their co-occurring social identities for Black, Latinx, and non-Latinx white youth in the Adolescent Brain Cognitive Development (ABCD) Study.

Objective: The primary aim of this study was to assess and adjust for measurement non-equivalence (bias) by sex, race/ethnicity, and co-occurring social identities (sex x race/ethnicity) for the Marijuana Effect Expectancies Questionnaire-Brief (MEEQ-B) among Black, Latinx, and Non-Latinx white youth. The second aim was to determine how group comparisons change after accounting for possible measurement bias.

Method: Black, Latinx, and Non-Latinx white youth from the Adolescent Brain and Cognitive Development Study Follow-up 3 (n=8,982; mean age=12.

Analysis of Depression and Anxiety Scores Following Initiation of Elexacaftor/Tezacaftor/Ivacaftor in Adults With Cystic Fibrosis.

Objective: Elexacaftor/tezacaftor/ivacaftor (E/T/I) has provided life-changing pharmacotherapy for many people with cystic fibrosis (CF), but conflicting literature exists regarding the effect on mental health. While some reports suggest E/T/I may induce adverse psychiatric symptoms, others report improvements in mental health symptoms. To add to this growing body of knowledge, we retrospectively analyzed depression and anxiety symptoms before and after E/T/I initiation in adults with CF at a single large US CF center.

Feasibility of free-breathing F MRI image acquisition to characterize ventilation defects in CF and healthy volunteers at wash-in.

Purpose: To explore the feasibility of measuring ventilation defect percentage (VDP) using F MRI during free-breathing wash-in of fluorinated gas mixture with postacquisition denoising and to compare these results with those obtained through traditional Cartesian breath-hold acquisitions.

Methods: Eight adults with cystic fibrosis and 5 healthy volunteers completed a single MR session on a Siemens 3T Prisma. H Ultrashort-TE MRI sequences were used for registration and masking, and ventilation images with F MRI were obtained while the subjects breathed a normoxic mixture of 79% perfluoropropane and 21% oxygen (O ).

Dynamic Perfluorinated Gas MRI Shows Improved Lung Ventilation in People with Cystic Fibrosis after Elexacaftor/Tezacaftor/Ivacaftor: An Observational Study.

The availability of highly effective CFTR modulators is revolutionizing the treatment of cystic fibrosis (CF) and drastically improving outcomes. MRI-based imaging modalities are now emerging as highly sensitive endpoints, particularly in the setting of mild lung disease. Adult CF patients were recruited from a single center prior to starting treatment with E/T/I.