Publications by authors named "Margot O'Brien"

Article Synopsis
  • - The study examined how predicted and experienced rewards affect decision-making in healthy adolescents and those with obsessive-compulsive disorder (OCD), focusing on goal-directed actions and their underlying brain circuits.
  • - Healthy adolescents showed that both types of values influenced their decision-making through specific brain areas, while adolescents with OCD lacked responsiveness to these values and exhibited unusual brain activity patterns.
  • - The findings suggest that OCD alters the motivational processes that guide actions, highlighting distinct brain circuit functions that are impaired in individuals with the disorder.
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Cognitive behavior therapy (CBT) for young people with obsessive compulsive disorder (OCD) has recently been enhanced to target family environment factors. However, the process of change for OCD symptoms and family factors during treatment is not well understood. Uniquely, we explored patterns of change for OCD symptoms and a range of family variables throughout Baseline, Early, Mid, and Late treatment phases of family-based CBT (FCBT) for 15 young people with OCD using multiple informants.

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