Publications by authors named "Margo J Pybus"

Article Synopsis
  • * Clinical symptoms in mesocarnivores indicated central nervous system infections, with some survivors developing antibodies against H5N1, showing potential disease spread into mammals.
  • * The virus showed various genetic patterns and nearly 17% had mutations that could help adapt to mammalian hosts, emphasizing the importance of continuous monitoring for potential risks to human health.
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Article Synopsis
  • Researchers studied data on harvest management practices and chronic wasting disease (CWD) trends in mule deer across 36 regions in the US and Canada.
  • They found that higher harvest rates of adult male mule deer were linked to lower CWD prevalence, particularly in areas where initial prevalence was low.
  • The study suggests that effective and sustained harvest strategies can help manage CWD outbreaks, especially early in the epidemic, laying a foundation for future adaptive disease management practices.
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Thirty-seven adult female moose ( Alces alces) from 2 distinct but adjacent populations in Elk Island National Park (EINP), Alberta, Canada (19 in north EINP and 18 in south EINP), were fitted with mortality-sensing VHF radio-collars, and radio signals were acquired daily to ascertain mortality status. At capture, serum, whole blood, and feces were collected; pregnancy was determined; teeth were aged by visual inspection; and a portion of liver was assessed by ultrasound examination. Postmortem examination was conducted on 20 suitable carcasses.

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Giant liver fluke (Fascioloides magna) populations readily expand under suitable conditions. Although extirpated from the eastern slopes of the Canadian Rocky Mountains in the early 1960s, the fluke reappeared following natural spread through mountain passes from British Columbia. Herein, we assessed epizootiology of the fluke population two decades later.

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Epizootic hemorrhagic disease (EHD) virus serotype 2 was identified by reverse-transcription (RT)-PCR in a white-tailed deer (Odocoileus virginianus) found dead in southern Alberta in September 2013. Field observations indicate at least 50 deer, primarily white-tailed deer, and three pronghorn antelope (Antilocapra americana) died during a suspected localized EHD outbreak.

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Winter ticks (Dermacentor albipictus) on elk (Cervus elaphus canadensis) have recently increased in numbers in the Yukon, Canada, potentially posing risks to other indigenous host species in the region. To evaluate the regional source of winter ticks in the Yukon, we sequenced one nuclear (ITS-2) and two mitochondrial (16SrRNA and COI) genes, and genotyped 14 microsatellite loci from 483 winter tick specimens collected across North America. We analyzed genetic variation across the geographic and host ranges of this tick species with the use of variance partitioning, Bayesian clustering, and standard population genetic analyses.

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Chronic wasting disease (CWD) is a fatal disease of North American cervids that was first detected in a wild, hunter-shot deer in Saskatchewan along the border with Alberta in Canada in 2000. Spatially explicit models for assessing factors affecting disease detection are needed to guide surveillance and control programs. Spatio-temporal patterns in CWD prevalence can be complicated by variation in individual infection probability and sampling biases.

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Chronic wasting disease is a transmissible spongiform encephalopathy of cervids, similar to sheep scrapie that has only recently been detected in wild populations of white-tailed deer (Odocoileus virginianus) and mule deer (Odocoileus hemionus hemionus) in western Canada. Relatively little is known about local transmission dynamics of the disease or the potential for long-distance spread. We analysed the population genetic structure of over 2000 white-tailed deer sampled from Alberta, British Columbia, and Saskatchewan using microsatellite profiles and mtDNA sequencing to assess the relative risk of disease spread.

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Article Synopsis
  • The study focuses on the winter tick Dermacentor albipictus and its impact on ungulates like moose, highlighting the confusion caused by genetic variations among tick populations.
  • Researchers sequenced several mitochondrial and nuclear DNA markers from ticks sampled from different deer populations in Alberta to examine genetic variation and its relationship to physical traits.
  • The findings suggest that despite significant differences in mitochondrial DNA indicating potential separate species, other genetic and morphological analyses point to all sampled ticks belonging to a single species, underscoring the need for comprehensive methods in identifying species.
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Chronic wasting disease (CWD) is increasingly prevalent in multiple wild mule (Odocoileus hemionus) and white-tailed deer (O. virginianus) herds in North America. CWD was first found in Canadian wild mule deer in Saskatchewan in 2000 and has since spread into the neighboring province of Alberta.

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