The role of morphology in combination with ploidy analysis in characterizing early gestational abortion.

Morphology in combination with flow cytometry is an inexpensive and fast tool to characterize important reasons for early gestational loss. Early partial hydatidiform moles are especially difficult to identify as not all have developed the typical histological features of central cistern formation and trophoblastic hyperplasia of the chorionic villi. Angiomatoid formation of the blood vessels, irregular chorionic villi, diffuse villous stromal fibrosis, trophoblastic pseudoinclusions, and pleomorphic trophoblast at the implantation site have therefore been proposed as additional morphological criteria.

[Amniotic fluid insulin levels versus mean maternal blood glucose levels in gestational diabetes mellitus: an analysis of the neonatal outcome].

Purpose: To compare the obstetric and neonatal outcome in pregnancies complicated by gestational diabetes mellitus after amniocentesis for amniotic fluid insulin measurement or maternal blood glucose monitoring or both as selection criterion for therapy.

Material And Methods: In a retrospective study, 408 diabetic pregnancies were analyzed; 307 were treated with diet alone (group 1) and 101 with diet and insulin (group 2). Pearson's chi2 or Fisher's exact test was used to assess obstetric and anthropometric data within these groups, and p values <0.