Publications by authors named "Margijske H G van Roest"

The influence of socioeconomic inequalities in pancreatic cancer patients and especially its effect in patients who had a resection is not known. Hospital type in which resection is performed might also influence outcome. Patients diagnosed with pancreatic cancer from 1989 to 2011 (n = 34,757) were selected from the population-based Netherlands Cancer Registry.

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Objective: To study the impact of perineural growth as a prognostic factor in periampullary adenocarcinoma (pancreatic head, ampulla of Vater, distal bile duct, and duodenal carcinoma).

Summary Background Data: Pancreatic head carcinoma is considered to have the worst prognosis of the periampullary carcinomas. Several other prognostic factors for periampullary tumors have been identified, eg, lymph node status, free resection margins, tumor size and differentiation, and vascular invasion.

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Article Synopsis
  • The study aimed to evaluate former Buruli ulcer disease (BUD) patients to identify factors leading to functional limitations and impact on employment or education.
  • The research involved a validated questionnaire and interviews, revealing that 57% of participants experienced functional limitations nearly 4 years post-treatment.
  • Key risk factors included age, gender, type of lesions, and persistent wounds, which were linked to job loss and school dropout, highlighting the urgent need for rehabilitation programs.
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The reliability and validity of the earlier developed Buruli ulcer functional limitation score (BUFLS) questionnaire was assessed. Of 638 former Buruli ulcer patients (of 678 individuals examined), sufficient items on daily activities (>or= 13 of the 19) were applicable to calculate a score. To determine the validity, the functional limitation scores of the 638 individuals were compared with the global impression of the limitations, range of motion (ROM), and the social impact (change of occupation or education) of Buruli ulcer.

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