Publications by authors named "Marghie Murgo"
Background: Central venous access devices (CVADs) allow intravenous therapy, haemodynamic monitoring and blood sampling but many fail before therapy completion.
Objective: To quantify CVAD failure and complications; and identify risk factors.
Designs, Settings, And Participants: Secondary analysis of multicentre randomised controlled trial including patients aged ≥16 years with a non-tunnelled CVAD (NTCVAD), peripherally-inserted central catheter (PICC) or tunnelled CVAD (TCVAD).
Objectives: Arterial catheters (ACs) are critical for haemodynamic monitoring and blood sampling but are prone to complications. We investigated the incidence and risk factors of AC failure.
Methods: Secondary analysis of a multi-centre randomised controlled trial (ACTRN 12610000505000).
Background: The optimal duration of infusion set use to prevent life-threatening catheter-related bloodstream infection (CRBSI) is unclear. We aimed to compare the effectiveness and costs of 7-day (intervention) versus 4-day (control) infusion set replacement to prevent CRBSI in patients with central venous access devices (tunnelled cuffed, non-tunnelled, peripherally inserted, and totally implanted) and peripheral arterial catheters.
Methods: We did a randomised, controlled, assessor-masked trial at ten Australian hospitals.
Article Synopsis
- Vascular access devices (VADs) are essential for medical procedures, but their associated administration sets (AS) are often replaced every 3-4 days, which may unnecessarily increase costs and workload despite evidence supporting longer use.
- A randomized controlled trial is being conducted to compare the safety and effectiveness of AS replacement every 4 days versus every 7 days on the incidence of bloodstream infections (BSIs) in patients with various types of catheters over a period of 4 years.
- The study aims to determine not only the primary outcome of VAD-related BSIs but also secondary factors like cost and device colonization rates, with strict ethical guidelines in place for dissemination of results.