Serum osteocalcin and parathyroid hormone in healthy children assessed with two new automated assays.

Background: The recent introduction of new automated assays needs careful definition of reference values in healthy children. The aim of this study was to determine serum parathyroid hormone (PTH) and osteocalcin in a large group of healthy children according to age.

Methods: We selected 2,288 healthy children (1,079 girls, 1,209 boys), aged 2-16 years.

Phenotypic APC resistance as a marker of hypercoagulability in primitive cerebral lymphoma.

Unlabelled: Thrombosis is the most frequent complication and the second cause of death in patients with malignant disease. Primary central nervous system non-Hodgkin's lymphoma represents a rare pathology. Resistance to APC is usually linked to a factor V (FV) gene mutation changing an Arg 506 to a Gln in the APC cleavage site.