Publications by authors named "Margherita Errico"
Article Synopsis
- Duchenne muscular dystrophy (DMD) is a progressive genetic disorder that currently has no cure, and its management relies on physiotherapy and medications to slow progression.
- Gene therapy presents a promising treatment option but requires a well-organized delivery system, such as the hub-and-spoke model, to effectively support DMD patients in Italy.
- A study mapped existing DMD centers in Italy, evaluated their readiness for gene therapy, and identified areas for improvement, ultimately proposing a flexible organizational model to enhance patient care.
Article Synopsis
- The paper discusses the challenge of balancing early access to innovative cancer therapies with thorough value assessment in Italy, noting that the country lacks a formal strategy for such medicines.
- A scoping review and expert interviews were conducted to explore early access strategies, with a quantitative analysis providing insights into the clinical and economic impacts of innovative oncology drugs.
- The findings suggest that adapting early access models from Germany and France could be beneficial for Italy, and the study calls for ongoing discussions about the advantages and potential drawbacks of implementing these schemes.
Article Synopsis
- A study was conducted to see what people living with HIV think about long-acting medications that could replace their daily pills.
- Most participants had a good relationship with their current treatments, but many felt that taking daily pills limited their freedom.
- A large number of patients were interested in long-acting treatments, with many preferring to get their injections at home rather than in a hospital, suggesting that this new treatment could make managing their health easier.
Background: Obesity is a complex health disorder that significantly increases the risk of several chronic diseases, and it has been associated with a 5-20-year decrease in life expectancy. The prevalence of obesity is increasing steadily worldwide and Italy follows this trend with an increase of almost 30% in the adult obese population in the last 3 decades. Previous studies estimated that 2-4% of the total health expenditure in Europe is attributed to obesity and it is projected to double by 2050.
View Article and Find Full Text PDFIntroduction: The use of oral tenofovir/emtricitabine (FTC/TDF) for pre-exposure prophylaxis (PrEP) among high-risk people without Human Immunodeficiency Virus (HIV), is emerging as an innovative strategy to decrease HIV epidemic. The study aims at evaluating the implications related to PrEP introduction, from a multidimensional point of view, as required by Health Technology Assessment (HTA) approach, with a particular attention on sustainability and social factors, influencing PrEP implementation.
Methods: An analysis was conducted involving 35 Italian Infectious Disease Departments.
This systematic review aims to summarize epigenome-wide studies on aberrant DNA methylation and its association with survival in patients with gastrointestinal adenocarcinoma. The 15 studies identified showed a large variety of methodological approaches for the identification of prognostic epigenetic markers from genome-wide methylation analyses. None of the findings were reported by more than one study in this systematic review.
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