Publications by authors named "Margherita De Biase"

Article Synopsis
  • The study investigates the potential relationship between autism spectrum disorder (ASD) and joint hypermobility (JH) in a cohort of 67 non-syndromic children, aged 2-18 years, with varying levels of cognitive impairment and autism severity.
  • Findings reveal that a noteworthy percentage (63% of ages 2-4 and 73% of ages 5+) of ASD patients display significant signs of hypermobility.
  • The study concludes that joint hypermobility might be a relevant characteristic in ASD patients, suggesting that it should be evaluated to enhance rehabilitation strategies, though no strong link was found between hypermobility and cognitive or autism severity scores.
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Assessing and improving walking abilities is considered one of the most important functional goals of physical therapy in children with cerebral palsy. However, there is still a gap in knowledge regarding the efficacy of treatment targeting the walking capacity of children with CP, as well as their responsiveness to the treatment. The 6 min walk test (6MWT) is a reliable tool to measure this function in children with CP, although less has been known about its potential efficacy to assess changes in the walking abilities associated with interventions.

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Perinatal stroke is related to possible differences in predisposing factors and outcomes between acutely and retrospectively diagnosed cases. In most cases, there are different risk factors and infections that could play an important role. Thus far, different clinical manifestations have been reported in children presenting with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), ranging from asymptomatic status to severe disease sustained by an immune-mediated inflammatory response.

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Article Synopsis
  • Orthorexia nervosa (ON) is characterized by an unhealthy obsession with healthy eating, raising questions about whether it's a lifestyle choice or a psychiatric disorder.
  • The study reviewed literature from 2015 to 2022, finding mixed evidence about ON's classification and its links to eating disorders (EDs) and obsessive-compulsive disorder (OCD).
  • Overall, the relationship between ON, EDs, and OCD remains complicated, highlighting the need for future research to clarify its clinical significance and progression.
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Children with developmental coordination disorder (DCD) and joint hypermobility could present an overlap of symptoms and motor functional difficulties. The link between these two clinical conditions has not yet been clarified. Recent studies reported a high incidence (30-50%) of motor delay in children who are referred to hypermobility and of enhanced joint hypermobility in children with DCD.

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