Publications by authors named "Margherita Chiari"
Article Synopsis
- A case report details a six-year-old girl with Rubinstein-Taybi syndrome, outlining her symptoms and the clinical settings where she developed her communication skills.
- A long-term, multidisciplinary intervention was implemented from 2014 to 2020, involving various therapies and active participation from her family and school.
- Although she still tests below average, significant progress in attention, communication, and functional skills has been achieved, highlighting the need for early genetic diagnosis and personalized rehabilitation programs for effective treatment.
Late recovery of consciousness in vegetative state is considered as an exceptional outcome and has been reported prevalently in patients who suffered a traumatic brain injury. In these patients, the benefits of prolonging the rehabilitation, aimed at the recovery of autonomy in basic everyday activities, has been demonstrated. Here, we describe the application of an intensive multi-professional rehabilitation program carried out on a young female patient, with exceptionally late recovery of consciousness, specifically, after 7 years of vegetative state due to severe brain hemorrhage.
View Article and Find Full Text PDFBackground: There is evidence that channelopathies are the cause of many different neurological diseases. The epileptic perinatal encephalopathy due to mutation in the KCNQ2 gene is a rare disease involving severe tetraparesis and cerebral visual impairment. Diseases of this kind are associated with severe disability that involves multiple systems and requires accurate genetic diagnosis and early multidisciplinary care once clinical stability is reached.
View Article and Find Full Text PDFPrimary Objective: To report consistent recovery of consciousness to a state of severe disability in a young patient after 7 years in vegetative state due to severe acquired brain injury, with reflections on protraction of intensive care and expert follow-up for the purpose of intercepting possible, albeit infrequent, cases of late recovery of consciousness.
Research Design: Single case study Methods: This study describes the 9-year history of a healthy 15-year-old who suffered cerebellar haemorrhage due to rupture of an arteriovenous malformation, followed by a brief period of coma then protracted vegetative state; late stabilization of general condition with resolution of neurosurgical complications. Clinical monitoring employed scales for structured assessment of severe disability and disorders of consciousness.