Publications by authors named "Margaux Quiniou"
The organization of microtubules into a mitotic spindle is critical for animal cell proliferation and involves the cooperation of hundreds of proteins whose molecular roles and regulation are not fully understood. The protein product of the Drosophila gene abnormal spindle, Asp, is a microtubule-associated protein required for correct mitotic spindle formation. To better understand the contribution of Asp to microtubule organization during spindle formation, we reverse-engineered flies to express a version of Asp (Asp), predicted to have lost its ability to bind the phosphatase trimer PP2A-B56.
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- - A survey of aging researchers revealed significant disagreement on key questions about aging, such as its definition, causes, onset, and rejuvenation, indicating a lack of consensus in the field.
- - Researchers have varying interpretations of what constitutes "aging," leading to different experimental approaches and priorities, which complicates the understanding and study of the aging process.
- - The findings highlight the necessity for clearer definitions and targeted goals within aging research, as well as strategies to address ongoing disagreements, in hopes of advancing the field.