Publications by authors named "Margaux Beretta"
Article Synopsis
- The study addresses the challenges in synthesizing glycopyranosyl nucleosides, specifically focusing on improving glycosylation methods for pyrimidine bases.
- Researchers successfully synthesized peptidonucleosides by glycosylating various pyrimidine nucleobases with specially modified glucopyranosyl donors that have an azide group.
- The investigation into different anomeric leaving groups revealed that using a sulfoxide donor and trimethylsilyl triflate yielded the highest success rates in the synthesis process.
The three-component Petasis borono-Mannich reaction starting with easily accessible N-protected α-amino aldehydes produces efficiently and diastereoselectively 1,2-trans-diamines with an enantiomeric excess of up to 98%.
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