Publications by authors named "Margarita T Angelova"
Page 1 of 1
Synopsis of recent research by authors named "Margarita T Angelova"
Margarita T Angelova's research predominantly focuses on the molecular mechanisms of RNA modifications, particularly methylation, and their implications in neurodevelopmental disorders and cancer, with special attention to tRNA and its fragments.
Recent findings highlight the significance of the FTSJ1 enzyme in neuron morphology and cognitive performance, implicating defects in this methyltransferase in X-linked intellectual disability and possibly cancer.
The development of novel sequencing methods for methylome profiling (NT-seq) and analyses of non-coding RNA populations underscores her commitment to advancing our understanding of epitranscriptomics in various biological contexts, including neurodevelopment and cellular response to environmental cues.